Uncovering the structure–function relationship in spider silk

JL Yarger, BR Cherry, A Van Der Vaart - Nature Reviews Materials, 2018 - nature.com
All spiders produce protein-based biopolymer fibres that we call silk. The most studied of
these silks is spider dragline silk, which is very tough and relatively abundant compared with …

[HTML][HTML] Tuning the conformation and mechanical properties of silk fibroin hydrogels

N Johari, L Moroni, A Samadikuchaksaraei - European Polymer Journal, 2020 - Elsevier
Mechanical properties of biomaterials play an important role in their biological performance.
Among the most important parameters in designing of biomaterials, their structure and …

Simultaneously toughening and stiffening elastomers with octuple hydrogen bonding

Y Zhuo, Z Xia, Y Qi, T Sumigawa, J Wu… - Advanced …, 2021 - Wiley Online Library
Current synthetic elastomers suffer from the well‐known trade‐off between toughness and
stiffness. By a combination of multiscale experiments and atomistic simulations, a …

Advances in quantum mechanochemistry: electronic structure methods and force analysis

T Stauch, A Dreuw - Chemical Reviews, 2016 - ACS Publications
In quantum mechanochemistry, quantum chemical methods are used to describe molecules
under the influence of an external force. The calculation of geometries, energies, transition …

Analysis of the Structure of Bombyx mori Silk Fibroin by NMR

T Asakura, K Okushita, MP Williamson - Macromolecules, 2015 - ACS Publications
The past 15 years have seen a major increase in our understanding of the structure and
dynamics of Bombyx mori silk fibroin, largely as a result of NMR studies. We now have a …

On the strength of β-sheet crystallites of Bombyx mori silk fibroin

Y Cheng, LD Koh, D Li, B Ji… - Journal of the Royal …, 2014 - royalsocietypublishing.org
Silk fibroin, a natural multi-domain protein, has attracted great attention due to its superior
mechanical properties such as ultra-high strength and stretchability, biocompatibility, as well …

Bio-mimetic mechanisms of natural hierarchical materials: a review

Q Chen, NM Pugno - Journal of the mechanical behavior of biomedical …, 2013 - Elsevier
Natural selection and evolution develop a huge amount of biological materials in different
environments (eg lotus in water and opuntia in desert). These biological materials possess …

[HTML][HTML] Production of protein-based polymers in Pichia pastoris

MWT Werten, G Eggink, MAC Stuart, FA de Wolf - Biotechnology advances, 2019 - Elsevier
Materials science and genetic engineering have joined forces over the last three decades in
the development of so-called protein-based polymers. These are proteins, typically with …

What makes spider silk fibers so strong? From molecular-crystallite network to hierarchical network structures

G Xu, L Gong, Z Yang, XY Liu - Soft Matter, 2014 - pubs.rsc.org
A Hierarchical Network (HN) model of soft matter was put forward to explain the mechanical
properties of animal silk fibers. At the nano-micro level, the silk fibers consist of a bundle of …

Silk structure studied with nuclear magnetic resonance

T Asakura, Y Suzuki, Y Nakazawa, K Yazawa… - Progress in Nuclear …, 2013 - Elsevier
Recently, considerable attention has been paid to silks by a range of scientists from textile
engineers to polymer chemists and biomedical researchers. The application of native silk …