Emerging theranostic nanomaterials in diabetes and its complications
Y Liu, S Zeng, W Ji, H Yao, L Lin, H Cui… - Advanced …, 2022 - Wiley Online Library
Diabetes mellitus (DM) refers to a group of metabolic disorders that are characterized by
hyperglycemia. Oral subcutaneously administered antidiabetic drugs such as insulin …
hyperglycemia. Oral subcutaneously administered antidiabetic drugs such as insulin …
Hydrogels in emerging technologies for type 1 diabetes
Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …
painless manner for patients has remained a central focus of next-generation diabetes …
A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes
Transplantation of stem cell–derived β (SC-β) cells represents a promising therapy for type 1
diabetes (T1D). However, the delivery, maintenance, and retrieval of these cells remain a …
diabetes (T1D). However, the delivery, maintenance, and retrieval of these cells remain a …
Engineering superstable islets-laden chitosan microgels with carboxymethyl cellulose coating for long-term blood glucose regulation in vivo
H Li, W He, Q Feng, J Chen, X Xu, C Lv, C Zhu… - Carbohydrate …, 2024 - Elsevier
Islet transplantation to restore endogenous insulin secretion is a promising therapy for type 1
diabetes in clinic. However, host immune rejection seriously limits the survival of …
diabetes in clinic. However, host immune rejection seriously limits the survival of …
Engineered immunomodulatory accessory cells improve experimental allogeneic islet transplantation without immunosuppression
Islet transplantation has been established as a viable treatment modality for type 1 diabetes.
However, the side effects of the systemic immunosuppression required for patients often …
However, the side effects of the systemic immunosuppression required for patients often …
A zwitterionic polyurethane nanoporous device with low foreign‐body response for islet encapsulation
Encapsulation of insulin‐producing cells is a promising strategy for treatment of type 1
diabetes. However, engineering an encapsulation device that is both safe (ie, no cell escape …
diabetes. However, engineering an encapsulation device that is both safe (ie, no cell escape …
[HTML][HTML] A novel bioartificial pancreas fabricated via islets microencapsulation in anti-adhesive core-shell microgels and macroencapsulation in a hydrogel scaffold …
H Li, Y Shang, Q Feng, Y Liu, J Chen, H Dong - Bioactive Materials, 2023 - Elsevier
Islets transplantation is a promising treatment for type 1 diabetes mellitus. However, severe
host immune rejection and poor oxygen/nutrients supply due to the lack of surrounding …
host immune rejection and poor oxygen/nutrients supply due to the lack of surrounding …
Engineering the vasculature for islet transplantation
The microvasculature in the pancreatic islet is highly specialized for glucose sensing and
insulin secretion. Although pancreatic islet transplantation is a potentially life-changing …
insulin secretion. Although pancreatic islet transplantation is a potentially life-changing …
A safe, fibrosis‐mitigating, and scalable encapsulation device supports long‐term function of insulin‐producing cells
Encapsulation and transplantation of insulin‐producing cells offer a promising curative
treatment for type 1 diabetes (T1D) without immunosuppression. However, biomaterials …
treatment for type 1 diabetes (T1D) without immunosuppression. However, biomaterials …
Biofabrication of a vascularized islet organ for type 1 diabetes
Islet transplantation is superior to extrinsic insulin supplementation in the treating severe
Type 1 diabetes. However, its efficiency and longevity are limited by substantial islet loss …
Type 1 diabetes. However, its efficiency and longevity are limited by substantial islet loss …