Background: Numerous physical, psychological, and emotional benefits have been
attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia …

For over 30 years, scientists have been investigating the phenomenon of pain suppression
upon exposure to unconditioned or conditioned stressful stimuli, commonly known as stress …

Pain in infancy influences pain reactivity in later life, but how and why this occurs is poorly
understood. Here we review the evidence for developmental plasticity of nociceptive …

Cannabis is the most used illicit drug worldwide and its medicinal use is under discussion,
being regulated in several countries. However, the psychotropic effects of Δ 9 …

The endocannabinoid system, consisting of the cannabinoid 1 receptor (CB 1 R) and
cannabinoid 2 receptor (CB 2 R), endogenous cannabinoid ligands (endocannabinoids) …

Preparations of the Cannabis sativa plant have been used to analgesic effect for millenia,
but only in recent decades has the endogenous system responsible for these effects been …

GABA A receptors are ligand-gated ion channels composed of five subunits that can be
opened by GABA and be modulated by multiple pharmacologically and clinically important …

In this review, I will consider the dual nature of Cannabis and cannabinoids. The duality
arises from the potential and actuality of cannabinoids in the laboratory and clinic and the …

BACKGROUND AND PURPOSE Two non‐psychoactive cannabinoids, cannabidiol (CBD)
and cannabichromene (CBC), are known to modulate in vitro the activity of proteins involved …

GABAA receptors are the major ionotropic inhibitory neurotransmitter receptors. The
endocannabinoid system is a lipid signaling network that modulates different brain functions …