Oxindole has been shown to be a pharmacologically advantageous scaffold having many
biological properties that are relevant to medicinal chemistry. The simplicity and widespread …

Introduction: Spirooxindole, a unique and versatile scaffold, has been widely studied in
some fields such as pharmaceutical chemistry and synthetic chemistry. Especially in the …

Conspectus The oxindole scaffold is a privileged structural motif that is found in a variety of
bioactive targets and natural products. Moreover, derivatives of the oxindole structure are …

An unprecedented asymmetric acyl-carbamoylation of pendant alkenes tethered on aryl
carbamic chlorides with both aliphatic and aromatic aldehydes has been developed via the …

In this review we compare and discuss results of compounds already reported as anticancer
agents based on isatin-derivatives, metalated as well as non-metallated. Isatin compounds …

A novel Rh (III)-catalyzed cascade alkenyl C–H activation/[3+ 2] annulation/pinacol
rearrangement reaction of enaminones with iodonium ylides has been developed. This …

Oxindole derivatives are known for their great interest in the field of Medicinal Chemistry, as
they display vast biological activities. Recent efforts concerning the preparation of oxindole …

Abstract The first enantioselective Satoh–Miura‐type reaction is reported. A variety of C− N
axially chiral N‐aryloxindoles have been enantioselectively synthesized by an asymmetric …

The tandem cyclization of acrylamide with diselenides facilitated by electrochemical
oxidation was successfully developed. This strategy provided an environmentally friendly …

The synthetic application of (hetero) aryl radicals in organic synthesis has been known since
the last century. However, their applicability has significantly suffered from ineffective …