Staphylococcal and streptococcal superantigen exotoxins
AR Spaulding, W Salgado-Pabón… - Clinical microbiology …, 2013 - Am Soc Microbiol
This review begins with a discussion of the large family of Staphylococcus aureus and beta-
hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and …
hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and …
The bacterial superantigen and superantigen‐like proteins
The bacterial superantigens are protein toxins that bind to major histocompatibility complex
class II and T‐cell receptor to stimulate large numbers of T cells. The majority are produced …
class II and T‐cell receptor to stimulate large numbers of T cells. The majority are produced …
MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their …
Superantigens (SAgs) are potent exotoxins secreted by Staphylococcus aureus and
Streptococcus pyogenes. They target a large fraction of T cell pools to set in motion a …
Streptococcus pyogenes. They target a large fraction of T cell pools to set in motion a …
Staphylococcal enterotoxins and enterotoxin-like toxins with special reference to dairy products: An overview
N Benkerroum - Critical reviews in food science and nutrition, 2018 - Taylor & Francis
ABSTRACT Staphylococcal Enterotoxins (SEs) have been raising health concerns for food
safety due to their association with staphylococcal foodborne poisoning (SFP). As …
safety due to their association with staphylococcal foodborne poisoning (SFP). As …
Bacterial Superantigens Promote Acute Nasopharyngeal Infection by Streptococcus pyogenes in a Human MHC Class II-Dependent Manner
Establishing the genetic determinants of niche adaptation by microbial pathogens to specific
hosts is important for the management and control of infectious disease. Streptococcus …
hosts is important for the management and control of infectious disease. Streptococcus …
Gram‐positive bacterial superantigen outside‐in signaling causes toxic shock syndrome
AJ Brosnahan, PM Schlievert - The FEBS journal, 2011 - Wiley Online Library
Staphylococcus aureus and Streptococcus pyogenes (group A streptococci) are Gram‐
positive pathogens capable of producing a variety of bacterial exotoxins known as …
positive pathogens capable of producing a variety of bacterial exotoxins known as …
TCR recognition of peptide/MHC class II complexes and superantigens
EJ Sundberg, L Deng, RA Mariuzza - Seminars in immunology, 2007 - Elsevier
Major histocompatibility complex (MHC) class II molecules display peptides to the T cell
receptor (TCR). The ability of the TCR to discriminate foreign from self-peptides presented …
receptor (TCR). The ability of the TCR to discriminate foreign from self-peptides presented …
[HTML][HTML] Streptococcal superantigens: biological properties and potential role in disease
Superantigens (SAgs) are a family of highly potent mitogens that share the ability to trigger
excessive stimulation of human and other mammalian T lymphocytes. This leads to a …
excessive stimulation of human and other mammalian T lymphocytes. This leads to a …
[HTML][HTML] Streptococcus pyogenes Superantigens: Biological properties and potential role in disease
T Proft, JD Fraser - … Basic Biology to Clinical Manifestations [Internet …, 2022 - ncbi.nlm.nih.gov
Superantigens (SAgs) are a family of highly potent mitogens that share the ability to trigger
excessive stimulation of human and other mammalian T lymphocytes. This leads to a …
excessive stimulation of human and other mammalian T lymphocytes. This leads to a …
Structure of the superantigen Staphylococcal Enterotoxin B in complex with TCR and peptide–MHC demonstrates absence of TCR–peptide contacts
KEJ Rödström, K Elbing… - The Journal of …, 2014 - journals.aai.org
Superantigens are immune-stimulatory toxins produced by Staphylococcus aureus, which
are able to interact with host immune receptors to induce a massive release of cytokines …
are able to interact with host immune receptors to induce a massive release of cytokines …