Background Several studies report the role of Regulatory T-cells (Tregs) in the
pathophysiology of pregnancy adverse outcomes. Objective The aim of this systematic …

Preeclampsia is a pregnancy-specific disease which is characterized by abnormal
placentation, endothelial dysfunction, and systemic inflammation. Several studies have …

Immune checkpoint inhibition has resulted in significant efficacy across many cancer types,
including melanoma. Melanoma is the second most common cancer among those of …

The foetus can be regarded as a half‐allograft implanted into the maternal body. In a
successful pregnancy, the mother does not reject the foetus because of the immune …

Preeclampsia and peripartum cardiomyopathy (PPCM) are significant obstetric problems
that can arise during or after pregnancy. Both are known to be causes of maternal mortality …

The mechanisms that underlie the timing of labor in humans are largely unknown. In most
pregnancies, labor is initiated at term (≥ 37 weeks gestation), but in a signifiicant number of …

Background NKT cell population is a relatively well-characterized immune cell subset.
Numerous publications have characterized the phenotypical features of its subpopulations …

Early-onset preeclampsia is a common obstetrical disease with a potential genetic
background and is characterized by the predominance of Th1 immune response. However …

Epidemiological observations implicate insulin resistance as a predisposing factor in the
development of preeclampsia (PE). It is also well established that PE manifests in the …

The current review evaluates how inflammasomes and immune checkpoints are regulated in
pre-eclampsia (PE) associated with tuberculosis (TB) and Human Immune Deficiency Virus …