The changing landscape of HIV-associated kidney disease

NE Diana, S Naicker - Nature Reviews Nephrology, 2024 - nature.com
The HIV epidemic has devastated millions of people globally, with approximately 40 million
deaths since its start. The availability of antiretroviral therapy (ART) has transformed the …

Pathogenesis of HIV associated nephropathy in children and adolescents: taking a hard look 40 years later in the era of gene-environmental interaction

PE Ray, J Li, J Das, L Xu, J Yu… - American Journal of …, 2024 - journals.physiology.org
HIV-associated nephropathy (HIVAN) is a kidney disease that affects mainly people of
African ancestry with a high HIV-1 viral load. New antiretroviral therapies (ART) have been …

Idiopathic collapsing glomerulopathy is associated with APOL1 high-risk genotypes or Mendelian variants in most affected individuals in a highly admixed population

PD Neves, A Watanabe, EH Watanabe, AM Narcizo… - Kidney International, 2024 - Elsevier
Collapsing glomerulopathy (CG) is most often associated with fast progression to kidney
failure with an incidence apparently higher in Brazil than in other countries. However, the …

APOL1 nephropathy–a population genetics success story

O Tabachnikov, K Skorecki… - Current Opinion in …, 2024 - journals.lww.com
Notwithstanding remaining controversies and uncertainties, promising genomically precise
therapies targeted at APOL1 mRNA using antisense oligonucleotides (ASO), inhibitors of …

Kidney transplantation in people living with human immunodeficiency virus: An overview of the Australian experience

L McMullen, D Drak, G Basu, PT Coates… - …, 2024 - Wiley Online Library
Kidney transplantation in people living with HIV (PLWHIV) is occurring with increasing
frequency. Limited international data suggest comparable patient and graft survival in kidney …

Advances in the management of chronic kidney disease–a South African perspective

T Jardine, MR Davids, MY Chothia - Wits Journal of Clinical …, 2024 - scienceopen.com
Chronic kidney disease (CKD) represents a significant public health problem globally, and
there is evidence to suggest that the prevalence of CKD in sub-Saharan Africa is …