Crosstalk between protein post-translational modifications and phase separation

Y Liu, W Feng, Y Wang, B Wu - Cell Communication and Signaling, 2024 - Springer
The phenomenon of phase separation is quite common in cells, and it is involved in multiple
processes of life activities. However, the current research on the correlation between protein …

Naegleria genus pangenome reveals new structural and functional insights into the versatility of these free-living amoebae

A Dereeper, N Allouch, V Guerlais, M Garnier… - Frontiers in …, 2023 - frontiersin.org
Introduction Free-living amoebae of the Naegleria genus belong to the major protist clade
Heterolobosea and are ubiquitously distributed in soil and freshwater habitats. Of the 47 …

[HTML][HTML] Tracking of Ubiquitin Signaling through 3.5 Billion Years of Combinatorial Conjugation

AN Kaminskaya, AS Evpak, AA Belogurov Jr… - International Journal of …, 2024 - mdpi.com
Ubiquitination is an evolutionary, ancient system of post-translational modification of
proteins that occurs through a cascade involving ubiquitin activation, transfer, and …

Translocon Subunits of the COP9 Signalosome Complex Are a Central Hub for Regulating Multiple Photoresponsive Processes and Autophagic Flux in Magnaporthe …

L Lin, H Guo, W Batool, L Lin, J Cao, Q An… - Journal of Agricultural …, 2024 - ACS Publications
Photodependent processes, including circadian rhythm, autophagy, ubiquitination,
neddylation/deneddylation, and metabolite biosynthesis, profoundly influence microbial …

Synergy between a cytoplasmic vWFA/VIT protein and a WD40-repeat F-box protein controls development in Dictyostelium

AW Boland, E Gas-Pascual, H van der Wel… - Frontiers in Cell and …, 2023 - frontiersin.org
Like most eukaryotes, the pre-metazoan social amoeba Dictyostelium depends on the SCF
(Skp1/cullin-1/F-box protein) family of E3 ubiquitin ligases to regulate its proteome. In …

[HTML][HTML] Cullin-Conciliated Regulation of Plant Immune Responses: Implications for Sustainable Crop Protection

H Wang, Z Xie - Plants, 2024 - mdpi.com
Cullins are crucial components of the ubiquitin–proteasome system, playing pivotal roles in
the regulation of protein metabolism. This review provides insight into the wide-ranging …

COP9 signalosome complex subunit-7-mediated regulation of cAMP levels contributes to autophagic degradation and pathogenesis of rice blast fungus Magnaporthe …

L Lin, H Guo, W Batool, L Lin, J Cao, Q An, SR Aliyu… - bioRxiv, 2023 - biorxiv.org
Photo-dependent processes, including circadian rhythm, autophagy, ubiquitination,
neddylation/deneddylation, and metabolite biosynthesis, profoundly influence microbial …

Investigating the protein quality control pathways that prevent protein aggregation in the social amoeba Dictyostelium discoideum.

HN Haver - 2023 - search.proquest.com
A major hallmark of many neurodegenerative diseases is protein aggregation. Protein
aggregation occurs in part due to failure of protein quality control pathways. A better …

The Role of SKP1 Glycosylation in SCF Assembly and the Characterization of the Interaction of an F-Box Protein and Its Binding Partner

AW Boland - 2022 - search.proquest.com
Most eukaryotes depend on the SCF (Skp1/cullin-1/F-box protein) family of E3 ubiquitin
ligases to regulate its proteome. The SCF binds to specific substrates and poly-ubiquitinates …