Beyond the emerging field of oncological ultrasound molecular imaging, the recent
significant advancements in ultrasound and contrast agent technology have paved the way …

The delivery of chemotherapeutics to solid tumors using smart drug delivery systems
(SDDSs) takes advantage of the unique physiology of tumors (ie, disordered structure, leaky …

Abstract Connexin 43 (Cx43)-associated gap junctions form electrical and mechanical
conduits between adjacent ventricular cardiomyocytes, ensuring coordinate electrical …

Recent findings in the field of biomaterials and tissue engineering provide evidence that
surface immobilised growth factors display enhanced stability and induce prolonged …

Dysregulation of miRNA expression has been associated with many cardiovascular
diseases in animal models, as well as in patients. In the present review, we summarize …

Cardiac tissue engineering approaches can deliver large numbers of cells to the damaged
myocardium and have thus increasingly been considered as a possible curative treatment to …

Aims Stromal interaction molecule 1 (STIM1) has been shown to control a calcium (Ca2+)
influx pathway that emerges during the hypertrophic remodelling of cardiomyocytes. Our aim …

Gene therapy provides an efficient approach for treatment of cardiovascular disease. To
realize the therapeutic effect, both efficient delivery to the target cells and sustained …

Early adaptive cardiac hypertrophy (EACH) is initially a compensatory process to optimize
pump function. We reported the emergence of Orai3 activity during EACH. This study aimed …

Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide.
Conventional therapies involving surgery or pharmacological strategies have shown limited …