Contributions of human ACE2 and TMPRSS2 in determining host–pathogen interaction of COVID-19
S Senapati, P Banerjee, S Bhagavatula… - Journal of genetics, 2021 - Springer
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is at present an
emerging global public health crisis. Angiotensin converting enzyme 2 (ACE2) and trans …
emerging global public health crisis. Angiotensin converting enzyme 2 (ACE2) and trans …
Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility
The COVID-19 pandemic has accounted for millions of infections and hundreds of thousand
deaths worldwide in a short-time period. The patients demonstrate a great diversity in …
deaths worldwide in a short-time period. The patients demonstrate a great diversity in …
[HTML][HTML] Hypotheses and facts for genetic factors related to severe COVID-19
Genome-wide association analysis allows the identification of potential candidate genes
involved in the development of severe coronavirus disease 2019 (COVID-19). Hence, it …
involved in the development of severe coronavirus disease 2019 (COVID-19). Hence, it …
Critical sequence hotspots for binding of novel coronavirus to angiotensin converter enzyme as evaluated by molecular simulations
The novel coronavirus (nCOV-2019) outbreak has put the world on edge, causing millions of
cases and hundreds of thousands of deaths all around the world, as of June 2020, let alone …
cases and hundreds of thousands of deaths all around the world, as of June 2020, let alone …
The role of genetic factors in the development of acute respiratory viral infection COVID-19: predicting severe course and outcomes
MM Minashkin, NY Grigortsevich, AS Kamaeva… - Biomedicines, 2022 - mdpi.com
The aim of this study was to identify single nucleotide variants in genes associated with
susceptibility to or severe outcomes of COVID-19. A total of 319 genomic DNA samples from …
susceptibility to or severe outcomes of COVID-19. A total of 319 genomic DNA samples from …
Host genetic risk factors associated with COVID-19 susceptibility and severity in Vietnamese
Since the emergence and rapid transmission of SARS-CoV-2, numerous scientific reports
have searched for the association of host genetic variants with COVID-19, but the data are …
have searched for the association of host genetic variants with COVID-19, but the data are …
[HTML][HTML] Genetic association of TMPRSS2 rs2070788 polymorphism with COVID-19 case fatality rate among Indian populations
Abstract SARS-CoV-2, the causative agent for COVID-19, an ongoing pandemic, engages
the ACE2 receptor to enter the host cell through S protein priming by a serine protease …
the ACE2 receptor to enter the host cell through S protein priming by a serine protease …
Analysis of ACE2 and TMPRSS2 coding variants as a risk factor for SARS‐CoV‐2 from 946 whole‐exome sequencing data in the Turkish population
Heterogeneity in symptoms associated with COVID‐19 in infected patients remains unclear.
ACE2 and TMPRSS2 gene variants are considered possible risk factors for COVID‐19. In …
ACE2 and TMPRSS2 gene variants are considered possible risk factors for COVID‐19. In …
Common cardiac medications potently inhibit ACE2 binding to the SARS-CoV-2 Spike, and block virus penetration and infectivity in human lung cells
H Caohuy, O Eidelman, T Chen, S Liu, Q Yang… - Scientific reports, 2021 - nature.com
To initiate SARS-CoV-2 infection, the Receptor Binding Domain (RBD) on the viral spike
protein must first bind to the host receptor ACE2 protein on pulmonary and other ACE2 …
protein must first bind to the host receptor ACE2 protein on pulmonary and other ACE2 …
Comparative genomics and integrated network approach unveiled undirected phylogeny patterns, co-mutational hot spots, functional cross talk, and regulatory …
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has resulted
in 92 million cases in a span of 1 year. The study focuses on understanding population …
in 92 million cases in a span of 1 year. The study focuses on understanding population …