Bone tissue has a remarkable ability to regenerate and heal itself. However, large bone
defects and complex fractures still present a significant challenge to the medical community …

Introduction One of the most challenging musculoskeletal complications in modern trauma
surgery is infection after fracture fixation (IAFF). Although infections are clinically obvious in …

Metallic fixation systems are currently the gold standard for fracture fixation but have
problems including stress shielding, palpability and temperature sensitivity. Recently …

Silk fibers spun by silkworms and spiders exhibit exceptional mechanical properties with a
unique combination of strength, extensibility and toughness. In contrast, the mechanical …

The locking plate and percutaneous crossing metallic screws and crossing absorbable
screws have been used clinically to treat intra-articular calcaneal fractures, but little is known …

Objectives: To compare the clinical outcomes of operative and nonoperative treatment for
displaced intra-articular calcaneal fractures (DIACFs). Data Sources: PubMed, Embase …

Fragility index (FI) is a metric used to interpret the results of randomized controlled trials
(RCTs), and describes the number of subjects that would need to be switched from event to …

Resorbable fixation systems have gained interest in orthopedics by avoiding secondary
surgery and stress shielding, but lack of enough bioactivity. Herein, we fabricated resorbable …

Implant-associated infections and non-absorbing materials are two important reasons for a
second surgical procedure to remove internal fixation devices after an orthopedic internal …

As a natural high-performance material with a unique hierarchical structure, silk is endowed
with superior mechanical properties. However, the current approaches towards producing …