Clustered miRNAs and their role in biological functions and diseases

SP Kabekkodu, V Shukla, VK Varghese… - Biological …, 2018 - Wiley Online Library
MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

MicroRNAs as potential biomarkers in cancer: opportunities and challenges

H Lan, H Lu, X Wang, H Jin - BioMed research international, 2015 - Wiley Online Library
MicroRNAs (miRNAs) are a group of small noncoding RNAs (ncRNAs) that
posttranscriptionally regulate gene expression by targeting their corresponding messenger …

The emerging role of microRNAs and long noncoding RNAs in drug resistance of hepatocellular carcinoma

L Wei, X Wang, L Lv, J Liu, H Xing, Y Song, M Xie… - Molecular Cancer, 2019 - Springer
Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and the
second most lethal human cancer. A portion of patients with advanced HCC can significantly …

[HTML][HTML] Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming

R Mattioli, A Ilari, B Colotti, L Mosca, F Fazi… - Molecular Aspects of …, 2023 - Elsevier
Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

MicroRNAs in the pathogenesis of hepatocellular carcinoma: a review

A Morishita, K Oura, T Tadokoro, K Fujita, J Tani… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is one of the most frequently occurring
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …

Pregnancy-associated miRNA-clusters

DM Morales-Prieto, S Ospina-Prieto… - Journal of reproductive …, 2013 - Elsevier
MicroRNAs (miRNAs) are expressed in the placenta and can be detected in maternal
plasma. An increasing number of studies have been published on the cellular origin …

MicroRNAs in placental health and disease

JF Mouillet, Y Ouyang, CB Coyne… - American journal of …, 2015 - Elsevier
MicroRNAs (miRNAs) constitute a large family of small noncoding RNAs that are encoded
by the genomes of most organisms. They regulate gene expression through …

Exosomes and hepatocellular carcinoma: from bench to bedside

R Sasaki, T Kanda, O Yokosuka, N Kato… - International journal of …, 2019 - mdpi.com
As hepatocellular carcinoma (HCC) usually occurs in the background of cirrhosis, which is
an end-stage form of liver diseases, treatment options for advanced HCC are limited, due to …

Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR

CL Kleinman, N Gerges, S Papillon-Cavanagh… - Nature …, 2014 - nature.com
Embryonal tumors with multilayered rosettes (ETMRs) are rare, deadly pediatric brain
tumors characterized by high-level amplification of the microRNA cluster C19MC,. We …

ETMR: a tumor entity in its infancy

S Lambo, K von Hoff, A Korshunov, SM Pfister… - Acta …, 2020 - Springer
Abstract Embryonal tumor with Multilayered Rosettes (ETMR) is a relatively rare but typically
deadly type of brain tumor that occurs mostly in infants. Since the discovery of the …