In Silico Studies of Some Isoflavonoids as Potential Candidates against COVID-19 Targeting Human ACE2 (hACE2) and Viral Main Protease (Mpro)

MS Alesawy, AE Abdallah, MS Taghour, EB Elkaeed… - Molecules, 2021 - mdpi.com
The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the “COVID-
19” disease that has been declared by WHO as a global emergency. The pandemic, which …

A Review of the Popular Uses, Anatomical, Chemical, and Biological Aspects of Kalanchoe (Crassulaceae): A Genus of Plants Known as “Miracle Leaf”

E Assis de Andrade, I Machinski, AC Terso Ventura… - Molecules, 2023 - mdpi.com
Species of the genus Kalanchoe have a long history of therapeutic use in ethnomedicine
linked to their remarkable healing properties. Several species have chemical and …

Isolation and In Silico Anti-SARS-CoV-2 Papain-Like Protease Potentialities of Two Rare 2-Phenoxychromone Derivatives from Artemisia spp.

YM Suleimen, RA Jose, RN Suleimen, C Arenz… - Molecules, 2022 - mdpi.com
Two rare 2-phenoxychromone derivatives, 6-demethoxy-4-O-capillarsine (1) and tenuflorin
C (2), were isolated from the areal parts of Artemisia commutata and A. glauca, respectively …

Methanolic Phoenix dactylifera L. Extract Ameliorates Cisplatin-Induced Hepatic Injury in Male Rats

HN Gad El-Hak, HS Mahmoud, EA Ahmed… - Nutrients, 2022 - mdpi.com
This study investigated the ameliorative potential of methanolic date flesh extract (MDFE)
against cisplatin-induced hepatic injury. Twenty male rats (weighing 180–200 g) were …

In Vitro and In Vivo Studies of Anti-Lung Cancer Activity of Artemesia judaica L. Crude Extract Combined with LC-MS/MS Metabolic Profiling, Docking Simulation and …

MS Goda, MS Nafie, BM Awad, MS Abdel-Kader… - Antioxidants, 2021 - mdpi.com
Artemisia judaica L.(Family: Asteraceae) exhibited antioxidant, anti-inflammatory, and
antiapoptotic effects. The in vitro cytotoxic activity of A. judaica ethanolic extract was …

Elucidation of Natural Components of Gardenia thunbergia Thunb. Leaves: Effect of Methanol Extract and Rutin on Non-Alcoholic Fatty Liver Disease

EM El-Shial, A Kabbash, M El-Aasr, OA El-Feky… - Molecules, 2023 - mdpi.com
The rising prevalence of non-alcoholic fatty liver disease NAFLD has strained the healthcare
system. Natural products could solve this problem, so the current study focused on the …

Comprehensive In Silico Screening of the Antiviral Potentialities of a New Humulene Glucoside from Asteriscus hierochunticus against SARS‐CoV‐2

VO Imieje, AA Zaki, AM Metwaly, AE Mostafa… - Journal of …, 2021 - Wiley Online Library
Chromatographic fractionation of the methanolic extract of Asteriscus hierochunticus whole
plant led to the identification of a new humulene glucoside (1). The chemical structure of the …

[HTML][HTML] The potential anti-Alzheimer's activity of Oxalis corniculata Linn. Methanolic extract in experimental rats: Role of APOE4/LRP1, TLR4/NF-κβ/NLRP3, Wnt 3/β …

K Abu-Elfotuh, AME Hamdan, SA Mohamed… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Oxalis corniculata (O. corniculata) is a member of
Oxalidaceae family, widely distributed in Asia, Europe, America, and Africa, used extensively …

Plicosepalus acacia Extract and Its Major Constituents, Methyl Gallate and Quercetin, Potentiate Therapeutic Angiogenesis in Diabetic Hind Limb Ischemia: HPTLC …

AR Abdel-Hamed, ET Mehanna, RM Hazem, JM Badr… - Antioxidants, 2021 - mdpi.com
Plicosepalus acacia (Fam. Loranthaceae) has been reported to possess hypoglycemic,
antioxidant, antimicrobial, and anti-inflammatory effects. Liquid chromatography combined …

Antitrypanosomal, Antitopoisomerase-I, and Cytotoxic Biological Evaluation of Some African Plants Belonging to Crassulaceae; Chemical Profiling of Extract Using …

MM Hegazy, WM Afifi, AM Metwaly, MM Radwan… - Molecules, 2022 - mdpi.com
In our continuous study for some African plants as a source for antitrypanosomally and
cytotoxic active drugs, nine different plants belonging to the Crassulaceae family have been …