Effects and mechanisms of resveratrol on aging and age‐related diseases

DD Zhou, M Luo, SY Huang, A Saimaiti… - Oxidative medicine …, 2021 - Wiley Online Library
The aging of population has become an issue of great concern because of its rapid
increase. Aging is an important risk factor of many chronic diseases. Resveratrol could be …

Cancer cachexia: molecular mechanisms and treatment strategies

T Setiawan, IN Sari, YT Wijaya, NM Julianto… - Journal of Hematology & …, 2023 - Springer
Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …

The beneficial therapeutic effects of plant‐derived natural products for the treatment of sarcopenia

M Bagherniya, A Mahdavi… - Journal of Cachexia …, 2022 - Wiley Online Library
Sarcopenia is an age‐related muscle disorder typically associated with a poor quality of life.
Its definition has evolved over time, and several underlying causes of sarcopenia in the …

Quercetin and related polyphenols: new insights and implications for their bioactivity and bioavailability

K Kawabata, R Mukai, A Ishisaka - Food & function, 2015 - pubs.rsc.org
The physiological functions and bioavailability of flavonoids have been widely investigated
since their bioactivities were identified about 80 years ago. Quercetin is a typical flavonoid …

Polyphenols and their effects on muscle atrophy and muscle health

T Nikawa, A Ulla, I Sakakibara - Molecules, 2021 - mdpi.com
Skeletal muscle atrophy is the decrease in muscle mass and strength caused by reduced
protein synthesis/accelerated protein degradation. Various conditions, such as denervation …

Experimental models of sarcopenia: bridging molecular mechanism and therapeutic strategy

S Mankhong, S Kim, S Moon, HB Kwak, DH Park… - Cells, 2020 - mdpi.com
Sarcopenia has been defined as a progressive decline of skeletal muscle mass, strength,
and functions in elderly people. It is accompanied by physical frailty, functional disability …

[HTML][HTML] Resveratrol prevents sarcopenic obesity by reversing mitochondrial dysfunction and oxidative stress via the PKA/LKB1/AMPK pathway

Y Huang, X Zhu, K Chen, H Lang, Y Zhang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Background: The concept of sarcopenic obesity refers to low muscle mass coupled with high
adiposity in older adults. Sarcopenic obesity is a new medical challenge that imposes …

Regulation of satellite cell function in sarcopenia

SE Alway, MJ Myers, JS Mohamed - Frontiers in aging neuroscience, 2014 - frontiersin.org
The mechanisms contributing to sarcopenia include reduced satellite cell (myogenic stem
cell) function that is impacted by the environment (niche) of these cells. Satellite cell function …

Inhibition of NF-κB signaling pathway by resveratrol improves spinal cord injury

L Xu, BOA Botchway, S Zhang, J Zhou… - Frontiers in …, 2018 - frontiersin.org
Spinal cord injury (SCI) can have a significant impact on an individual's life. Herein, we
discuss how resveratrol improves SCI by inhibiting nuclear factor kappa-light-chain …

The role of metabolic remodeling in macrophage polarization and its effect on skeletal muscle regeneration

F De Santa, L Vitiello, A Torcinaro… - Antioxidants & redox …, 2019 - liebertpub.com
Significance: Macrophages are crucial for tissue homeostasis. Based on their activation,
they might display classical/M1 or alternative/M2 phenotypes. M1 macrophages produce pro …