Insights into the interaction mechanism of acid phosphatase from Lateolabrax japonicus livers and rosmarinic acid using multispectroscopy and molecular docking
Y Li, Y Li, N Zhao, D Shi, S Yi, J Li - Food Chemistry, 2023 - Elsevier
Acid phosphatase (ACP) is a key enzyme that hydrolyzes inosinic acid. The mechanisms
underlying the interaction between rosmarinic acid (RA) and ACP and the inhibition of the …
underlying the interaction between rosmarinic acid (RA) and ACP and the inhibition of the …
Theoretical study on the design of allosteric inhibitors of diabetes associated protein PTP1B
J Zhan, Z Liu, H Gao - Frontiers in Pharmacology, 2024 - frontiersin.org
The protein tyrosine phosphatase 1B (PTP1B) is a critical therapeutic target for type 2
diabetes mellitus (T2DM). Many PTP1B inhibitors have been reported, however, most of …
diabetes mellitus (T2DM). Many PTP1B inhibitors have been reported, however, most of …
Virtual screening, molecular simulations and bioassays: Discovering novel microsomal prostaglandin E Synthase-1 (mPGES-1) inhibitors
ZY Babaoglu, D Kilic - Computers in Biology and Medicine, 2023 - Elsevier
Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible prostaglandin E
synthase expressed following exposure to pro-inflammatory stimuli. The mPGES-1 enzyme …
synthase expressed following exposure to pro-inflammatory stimuli. The mPGES-1 enzyme …
Discovery of inhibitors of protein tyrosine phosphatase 1B contained in a natural products library from Mexican medicinal plants and fungi using a combination of …
M Díaz-Rojas, M González-Andrade… - Frontiers in …, 2023 - frontiersin.org
This work aimed to discover protein tyrosine phosphatase 1B (PTP1B) inhibitors from a
small molecule library of natural products (NPs) derived from selected Mexican medicinal …
small molecule library of natural products (NPs) derived from selected Mexican medicinal …
Ball milling extraction as a green and efficient approach for the extraction of sixteen xanthone-type QR-2 and PTP1B inhibitors from Garcinia mangostana L. pericarp
J Li, W Su, Y Pei, H Li, K Liu, J Ai, X Weng, H Fu… - Food Analytical …, 2023 - Springer
Mangosteen (Garcinia mangostana L.) pericarp is a potential source of bioactive xanthones.
These xanthones can exert anti-diabetic and anti-malarial effects by inhibiting the activity of …
These xanthones can exert anti-diabetic and anti-malarial effects by inhibiting the activity of …