[HTML][HTML] NO as a signalling molecule in the nervous system
JV Esplugues - British journal of pharmacology, 2002 - ncbi.nlm.nih.gov
NO was first characterized in the CNS as the intercellular messenger mediating the increase
in cyclic GMP levels that follows activation of glutamate receptors (Garthwaite et al., 1988) …
in cyclic GMP levels that follows activation of glutamate receptors (Garthwaite et al., 1988) …
[PDF][PDF] Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1, 2, 4] oxadiazolo [4, 3-a] quinoxalin-1-one.
J Garthwaite, E Southam, CL Boulton, EB Nielsen… - Molecular …, 1995 - Citeseer
In brain and other tissues, nitric oxide (NO) operates as a diffusible second messenger that
stimulates the soluble form of the guanylyl cyclase enzyme and so elicits an accumulation of …
stimulates the soluble form of the guanylyl cyclase enzyme and so elicits an accumulation of …
Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor …
H Kimura, A Weisz, Y Kurashima… - Blood, The Journal …, 2000 - ashpublications.org
Nitric oxide (NO) regulates production of vascular endothelial growth factor (VEGF) by
normal and transformed cells. We demonstrate that NO donors may up-regulate the activity …
normal and transformed cells. We demonstrate that NO donors may up-regulate the activity …
Models of the diffusional spread of nitric oxide: implications for neural nitric oxide signalling and its pharmacological properties
J Wood, J Garthwaite - Neuropharmacology, 1994 - Elsevier
Nitric oxide (NO) functions as a diffusible messenger molecule in many different tissues,
including the brain. To create a conceptual framework for understanding the behaviour of …
including the brain. To create a conceptual framework for understanding the behaviour of …
[HTML][HTML] Nitric oxide regulates cardiac Ca2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation.
PF Mery, C Pavoine, L Belhassen, F Pecker… - Journal of Biological …, 1993 - Elsevier
The effects of the nitric oxide (NO) donor 3-morpholino-sydnonimine (SIN-1) on the L-type
Ca2+ current (ICa) were examined in frog ventricular myocytes under basal and …
Ca2+ current (ICa) were examined in frog ventricular myocytes under basal and …
Multiple Mechanisms of Na+ Channel– Linked Long-QT Syndrome
Inheritable long-QT syndrome (LQTS) is a disease in which delayed ventricular
repolarization leads to cardiac arrhythmias and the possibility of sudden death. In the …
repolarization leads to cardiac arrhythmias and the possibility of sudden death. In the …
Nitric oxide induces rapid, calcium‐dependent release of vesicular glutamate and ATP from cultured rat astrocytes
A Bal‐Price, Z Moneer, GC Brown - Glia, 2002 - Wiley Online Library
Nitric oxide (NO; 1 μM) or an NO donor (500 μM diethylenetriamine‐nitric oxide, DETA‐
NONOate) caused rapid glutamate and ATP release from cultured rat cortical astrocytes. NO …
NONOate) caused rapid glutamate and ATP release from cultured rat cortical astrocytes. NO …
[图书][B] Nitric oxide in health and disease
J Lincoln, CHV Hoyle, G Burnstock - 1997 - books.google.com
Nitric oxide has a tantalizing role in health and disease: while many of its wide-ranging
effects are well known, there remains much more to explore and to learn about the …
effects are well known, there remains much more to explore and to learn about the …
Chemistry, Analysis, and Biological Roles ofS-Nitrosothiols
AR Anthony, P Rhodes - Analytical biochemistry, 1997 - Elsevier
The discovery of the several roles of nitric oxide (NO) 1 nitrosothiols have absorbancies in
the regions of 330–350 and 550–600 nm and these absorbancies can be in animal …
the regions of 330–350 and 550–600 nm and these absorbancies can be in animal …
Nitric Oxide Can Increase Heart Rate by Stimulating the Hyperpolarization-Activated Inward Current, If
P Musialek, M Lei, HF Brown, DJ Paterson… - Circulation …, 1997 - Am Heart Assoc
We investigated the chronotropic effect of increasing concentrations of sodium nitroprusside
(SNP, n= 8) or 3-morpholinosydnonimine (SIN-1, n= 6) in isolated guinea pig spontaneously …
(SNP, n= 8) or 3-morpholinosydnonimine (SIN-1, n= 6) in isolated guinea pig spontaneously …