Bacterial toxins active against mosquitoes: Mode of action and resistance

MHNL Silva-Filha, TP Romão, TMT Rezende… - Toxins, 2021 - mdpi.com
Larvicides based on the bacteria Bacillus thuringiensis svar. israelensis (Bti) and
Lysinibacillus sphaericus are effective and environmentally safe compounds for the control …

From synthesis to characterization of site-selective PEGylated proteins

LH Belén, CO Rangel-Yagui… - Frontiers in …, 2019 - frontiersin.org
Covalent attachment of therapeutic proteins to polyethylene glycol (PEG) is widely used for
the improvement of its pharmacokinetic and pharmacological properties, as well as the …

Towards toxin PEGylation: The example of rCollinein-1, a snake venom thrombin-like enzyme, as a PEGylated biopharmaceutical prototype

EL Pinheiro-Junior, J Boldrini-França… - International Journal of …, 2021 - Elsevier
PEGylation was firstly described around 50 years ago and has been used for more than 30
years as a strategy to improve the drugability of biopharmaceuticals. However, it remains …

[HTML][HTML] Mosquito-larvicidal Binary (BinA/B) proteins for mosquito control programs—advancements, challenges, and possibilities

M Sharma, V Kumar - Current Research in Insect Science, 2022 - Elsevier
The increasing global burden of mosquito-borne diseases require targeted, environmentally
friendly, and sustainable approaches for effective vector control without endangering the …

Receptor protein of Lysinibacillus sphaericus mosquito-larvicidal toxin displays amylomaltase activity

M Sharma, GD Gupta, V Kumar - Insect biochemistry and molecular biology, 2018 - Elsevier
The activated binary toxin (BinAB) from Lysinibacillus sphaericus binds to surface receptor
protein (Cqm1) on the midgut cell membrane and kills Culex quinquefasciatus larvae on …

Liposome-based study provides insight into cellular internalization mechanism of mosquito-larvicidal BinAB toxin

M Sharma, A Kumar, V Kumar - The Journal of Membrane Biology, 2020 - Springer
Glycosylphosphatidylinositols (GPIs) anchored proteins are commonly localized onto lipid
rafts. These extracellular proteins participate in a variety of cellular functions, including as …

Mosquito-larvicidal BinA toxin displays affinity for glycoconjugates: Proposal for BinA mediated cytotoxicity

M Sharma, GD Gupta, V Kumar - Journal of invertebrate pathology, 2018 - Elsevier
Lysinibacillus sphaericus parasporal BinAB toxin displays mosquito larvicidal activity
against Culex and Anopheles, but several Aedes species are refractory. Recently reported …

Advances in the use of entomopathogenic bacteria/microbial control agents (MCAs) as biopesticides in suppressing crop insect pests

T Rao, JL Jurat-Fuentes - Biopesticides for sustainable …, 2020 - api.taylorfrancis.com
Chapter 5 Page 1 http://dx.doi.org/10.19103/AS.2020.0073.06 © Burleigh Dodds Science
Publishing Limited, 2020. All rights reserved. Chapter 5 Advances in the use of …

[HTML][HTML] Bacillus thuringiensis y L. sphaericus como biocontroladores de A. aegypti y A. albopictus; vectores de virus del dengue y de la fiebre amarilla

A Aguilar Quintero, S Cardoso Pachón - Revista Med, 2023 - scielo.org.co
El dengue y la fiebre amarilla representan actualmente un problema de salud en los países
tropicales, en donde se busca que la población adopte medidas para evitar ser afectada por …

[PDF][PDF] Bacterial toxins active against mosquitoes: mode of action and resistance. Toxins. 2021; 13: 523

M Silva-Filha, TP Romão, TMT Rezende, KS Carvalho… - 2021 - academia.edu
Larvicides based on the bacteria Bacillus thuringiensis svar. israelensis (Bti) and
Lysinibacillus sphaericus are effective and environmentally safe compounds for the control …