Virus pandemics have happened, are happening and will happen again. In recent decades,
the rate of zoonotic viral spillover into humans has accelerated, mirroring the expansion of …

(1) Background: Indoor air pollution can affect the well-being and health of humans. Sources
of indoor pollution with particulate matter (PM) are outdoor particles and indoor causes, such …

The rapid and reliable recognition of nucleic acid sequences is essential to a broad range of
fields including genotyping, gene expression analysis, and pathogen screening. For viral …

Sample preparation is an essential step for nearly every type of biochemical analysis in use
today. Among the most important of these analyses is the diagnosis of diseases, since their …

Viral metagenomics has revolutionized our understanding for identification of unknown or
poorly characterized viruses. For that reason, metagenomic studies gave been largely …

Background: Diagnosis of infections in returning international travellers can be challenging
because of the broad spectrum of potential infectious etiologies potentially involved. Viral …

Hepatitis B virus (HBV) infection is a leading cause of hepatocellular carcinoma (HCC)
worldwide. The integration of HBV genomic DNA into the host genome occurs randomly …

Next-generation sequencing technologies have revolutionized the field of virology by
enabling the reading of complete viral genomes, extensive metagenomic studies, and the …

Metagenomics based on the next-generation sequencing (NGS) technique is a target-
independent assay that enables the simultaneous detection and genomic characterization of …

The huge genetic diversity of circulating viruses is a challenge for diagnostic assays for
emerging or rare viral diseases. High-throughput technology offers a new opportunity to …