The cell wall envelope of gram-positive bacteria is a macromolecular, exoskeletal organelle
that is assembled and turned over at designated sites. The cell wall also functions as a …

Streptomycetes, soil-dwelling mycelial bacteria that form sporulating aerial branches, have
an exceptionally large number of predicted secreted proteins, including many exported via …

One of the most salient features of Bacillus subtilis and related bacilli is their natural capacity
to secrete a variety of proteins into their environment, frequently to high concentrations. This …

Secretory proteins perform a variety of important “remote-control” functions for bacterial
survival in the environment. The availability of complete genome sequences has allowed us …

▪ Abstract The signal recognition particle (SRP) and its membrane-associated receptor (SR)
catalyze targeting of nascent secretory and membrane proteins to the protein translocation …

The basic machinery for the translocation of proteins into or across membranes is
remarkably conserved from Escherichia coli to humans. In eukaryotes, proteins are inserted …

The signal recognition particle (SRP) and its membrane-bound receptor (SR) deliver
membrane proteins and secretory proteins to the translocation channel in the plasma …

Proteins that perform their activity within the cytoplasmic membrane or outside this cell
boundary must be targeted to the translocation site prior to their insertion and/or …

The trimethylamine N‐oxide (TMAO) reductase of Escherichia coli is a soluble periplasmic
molybdoenzyme. The precursor of this enzyme possesses a cleavable N‐terminal signal …

In contrast to Gram-negative bacteria, secretory proteins of Gram-positive bacteria only need
to traverse a single membrane to enter the extracellular environment. For this reason, Gram …