Current state of the art for enhancing urine biomarker discovery

M Harpole, J Davis, V Espina - Expert review of Proteomics, 2016 - Taylor & Francis
Introduction: Urine is a highly desirable biospecimen for biomarker analysis because it can
be collected recurrently by non-invasive techniques, in relatively large volumes. Urine …

Proteomic technologies for the identification of disease biomarkers in serum: advances and challenges ahead

S Ray, PJ Reddy, R Jain, K Gollapalli, A Moiyadi… - …, 2011 - Wiley Online Library
Serum is an ideal biological sample that contains an archive of information due to the
presence of a variety of proteins released by diseased tissue, and serum proteomics has …

[HTML][HTML] Synthesis and swelling behavior of xanthan-based hydrogels

VB Bueno, R Bentini, LH Catalani, DFS Petri - Carbohydrate polymers, 2013 - Elsevier
In this work xanthan chains were crosslinked by esterification reaction at 165° C either in the
absence or in the presence of citric acid. Higher crosslinking density was obtained using …

Noninvasive precision screening of prostate cancer by urinary multimarker sensor and artificial intelligence analysis

H Kim, S Park, IG Jeong, SH Song, Y Jeong, CS Kim… - ACS …, 2020 - ACS Publications
Screening for prostate cancer relies on the serum prostate-specific antigen test, which
provides a high rate of false positives (80%). This results in a large number of unnecessary …

Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics

R Hüttenhain, M Soste, N Selevsek, H Röst… - Science translational …, 2012 - science.org
The rigorous testing of hypotheses on suitable sample cohorts is a major limitation in
translational research. This is particularly the case for the validation of protein biomarkers; …

[HTML][HTML] Hydrogel-based biosensors

K Völlmecke, R Afroz, S Bierbach, LJ Brenker, S Frücht… - Gels, 2022 - mdpi.com
There is an increasing interest in sensing applications for a variety of analytes in aqueous
environments, as conventional methods do not work reliably under humid conditions or they …

Label-free detection of tear biomarkers using hydrogel-coated gold nanoshells in a localized surface plasmon resonance-based biosensor

HR Culver, ME Wechsler, NA Peppas - ACS nano, 2018 - ACS Publications
The dependence of the localized surface plasmon resonance (LSPR) of noble-metal
nanomaterials on refractive index makes LSPR a useful, label-free signal transduction …

Growth hormone doping in sports: a critical review of use and detection strategies

GP Baumann - Endocrine reviews, 2012 - academic.oup.com
GH is believed to be widely employed in sports as a performance-enhancing substance. Its
use in athletic competition is banned by the World Anti-Doping Agency, and athletes are …

[HTML][HTML] Reactive oxygen species activate NFκB (p65) and p53 and induce apoptosis in RVFV infected liver cells

A Narayanan, M Amaya, K Voss, M Chung, A Benedict… - Virology, 2014 - Elsevier
Rift Valley fever virus (RVFV) infection is often associated with pronounced liver damage.
Previously, our studies revealed altered host phospho-signaling responses (NFκB, MAPK …

[HTML][HTML] Core-shell hydrogel particles harvest, concentrate and preserve labile low abundance biomarkers

C Longo, A Patanarut, T George, B Bishop, W Zhou… - PloS one, 2009 - journals.plos.org
Background The blood proteome is thought to represent a rich source of biomarkers for early
stage disease detection. Nevertheless, three major challenges have hindered biomarker …