Recent progress on polysaccharide-based hydrogels for controlled delivery of therapeutic biomolecules

MI Rial-Hermida, A Rey-Rico… - ACS Biomaterials …, 2021 - ACS Publications
A plethora of applications using polysaccharides have been developed in recent years due
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …

Polymeric materials, advances and applications in tissue engineering: a review

MC Socci, G Rodríguez, E Oliva, S Fushimi… - Bioengineering, 2023 - mdpi.com
Tissue Engineering (TE) is an interdisciplinary field that encompasses materials science in
combination with biological and engineering sciences. In recent years, an increase in the …

Extracellular matrix‐mimetic hydrogels for treating neural tissue injury: a focus on fibrin, hyaluronic acid, and elastin‐like polypeptide hydrogels

DW Nelson, RJ Gilbert - Advanced healthcare materials, 2021 - Wiley Online Library
Neurological and functional recovery is limited following central nervous system injury and
severe injury to the peripheral nervous system. Extracellular matrix (ECM)‐mimetic …

Bone mesenchymal stem cell-derived exosome-loaded injectable hydrogel for minimally invasive treatment of spinal cord injury

J Cheng, Z Chen, C Liu, M Zhong, S Wang, Y Sun… - …, 2021 - Taylor & Francis
Aim: Bone mesenchymal stem cell-derived exosomes (Exos) have been shown to exert
therapeutic effects in spinal cord injury (SCI). In this study, we aimed to apply bioengineering …

[HTML][HTML] Injectable, anti-inflammatory and conductive hydrogels based on graphene oxide and diacerein-terminated four-armed polyethylene glycol for spinal cord …

K Zhang, J Li, J Jin, J Dong, L Li, B Xue, W Wang… - Materials & Design, 2020 - Elsevier
Patients with spinal cord injury (SCI) often suffer from permanent disabilities because of the
low regeneration ability of adult axons. Hydrogels can serve as the scaffolding materials to …

Scavenging of reactive oxygen species can adjust the differentiation of tendon stem cells and progenitor cells and prevent ectopic calcification in tendinopathy

H Shen, L Cheng, Q Zheng, W Liu, Y Wang - Acta Biomaterialia, 2022 - Elsevier
Tendinopathy is a common disorder that leads to pain and impaired quality of life. Recent
studies revealed that osteogenic differentiation of tendon stem/progenitor cells (TSPCs) …

Harnessing the physicochemical properties of DNA as a multifunctional biomaterial for biomedical and other applications

A Chakraborty, SP Ravi, Y Shamiya, C Cui… - Chemical Society …, 2021 - pubs.rsc.org
The biological purpose of DNA is to store, replicate, and convey genetic information in cells.
Progress in molecular genetics have led to its widespread applications in gene editing, gene …

Anti‐VEGF‐R2 aptamer and RGD peptide synergize in a bifunctional hydrogel for enhanced angiogenic potential

T Roy, BD James, JB Allen - Macromolecular bioscience, 2021 - Wiley Online Library
Hydrogels have gained interest for use in tissue regeneration and wound healing because
of their absorbing and swelling properties as well as their ability to mimic the natural …

Research advances of biomaterials-based microenvironment-regulation therapies for repair and regeneration of spinal cord injury

Z Li, Q Wang, H Hu, W Zheng, C Gao - Biomedical Materials, 2021 - iopscience.iop.org
Traumatic spinal cord injury (SCI) usually results in restricted behaviour recovery and even
life-changing paralysis, accompanied with numerous complications. Pathologically, the …

Dancing with Nucleobases: Unveiling the Self-Assembly Properties of DNA and RNA Base-Containing Molecules for Gel Formation

PL Scognamiglio, C Vicidomini, GN Roviello - Gels, 2023 - mdpi.com
Nucleobase-containing molecules are compounds essential in biology due to the
fundamental role of nucleic acids and, in particular, G-quadruplex DNA and RNA in life …