Interstitial lung diseases

M Wijsenbeek, A Suzuki, TM Maher - The Lancet, 2022 - thelancet.com
Over 200 interstitial lung diseases, from ultra rare to relatively common, are recognised.
Most interstitial lung diseases are characterised by inflammation or fibrosis within the …

Diagnosis, course and management of hypersensitivity pneumonitis

M Hamblin, H Prosch… - European Respiratory …, 2022 - Eur Respiratory Soc
Hypersensitivity pneumonitis (HP) is a complex and heterogeneous interstitial lung disease
(ILD) that occurs when susceptible individuals develop an exaggerated immune response to …

Acute exacerbation of interstitial lung disease associated with rheumatic disease

F Luppi, M Sebastiani, C Salvarani… - Nature Reviews …, 2022 - nature.com
Interstitial lung disease (ILD) is a cause of morbidity and mortality in patients with rheumatic
diseases, such as connective-tissue diseases, rheumatoid arthritis and systemic vasculitis …

[HTML][HTML] Nintedanib in progressive interstitial lung diseases: data from the whole INBUILD trial

KR Flaherty, AU Wells, V Cottin… - European …, 2022 - Eur Respiratory Soc
Background The primary analysis of the INBUILD trial showed that in subjects with
progressive fibrosing interstitial lung diseases (ILDs), nintedanib slowed the decline in …

Immunomodulatory treatment of interstitial lung disease

L van den Bosch, F Luppi, G Ferrara… - … in Respiratory Disease, 2022 - journals.sagepub.com
Interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis (IPF) have an array
of immunomodulatory treatment options compared with IPF, due to their inflammatory …

Acute exacerbation of rheumatoid arthritis-associated interstitial lung disease: mortality and its prediction model

H Hozumi, M Kono, H Hasegawa, S Kato, Y Inoue… - Respiratory …, 2022 - Springer
Background Patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD),
like those with idiopathic pulmonary fibrosis (IPF), might develop an unexpected acute …

Incidence, risk factors, and prognosis of acute exacerbation of rheumatoid arthritis-associated interstitial lung disease: a systematic review and meta-analysis

M Xie, C Zhu, Y Ye - BMC Pulmonary Medicine, 2023 - Springer
Introduction Acute exacerbation (AE) is a devastating complication of rheumatoid arthritis-
associated interstitial lung disease (RA-ILD) and leads to high mortality. This study aimed to …

Acute exacerbation of fibrotic hypersensitivity pneumonitis: incidence and outcomes

J Kang, YJ Kim, J Choe, EJ Chae, JW Song - Respiratory Research, 2021 - Springer
Background Patients with fibrotic hypersensitivity pneumonitis (HP) show variable clinical
courses, and some experience rapid deterioration (RD), including acute exacerbation (AE) …

Emerging opportunities to treat idiopathic pulmonary fibrosis: Design, discovery, and optimizations of small-molecule drugs targeting fibrogenic pathways

W Luo, Y Gu, S Fu, J Wang, J Zhang, Y Wang - European Journal of …, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is the most common fibrotic form of idiopathic diffuse lung
disease. Due to limited treatment options, IPF patients suffer from poor survival. About ten …

COVID-19 and acute exacerbation of interstitial lung disease

Y Kondoh, K Kataoka, M Ando, Y Awaya… - Respiratory …, 2021 - Elsevier
We conducted a study to examine the effect of COVID-19 on the acute exacerbation of
interstitial lung disease (AE-ILD) early in the COVID-19 epidemic (January 1–April 30 …