Murine electrophysiological models of cardiac arrhythmogenesis

CLH Huang - Physiological reviews, 2017 - journals.physiology.org
Cardiac arrhythmias can follow disruption of the normal cellular electrophysiological
processes underlying excitable activity and their tissue propagation as coherent wavefronts …

Atrial arrhythmia, triggering events and conduction abnormalities in isolated murine RyR2‐P2328S hearts

JH King, Y Zhang, M Lei, AA Grace… - Acta …, 2013 - Wiley Online Library
Aim R y R 2 mutations are associated with catecholaminergic polymorphic tachycardia, a
condition characterized by ventricular and atrial arrhythmias. The present experiments …

Arrhythmic substrate, slowed propagation and increased dispersion in conduction direction in the right ventricular outflow tract of murine Scn5a+/− hearts

Y Zhang, L Guzadhur, K Jeevaratnam… - Acta …, 2014 - Wiley Online Library
Aim To test a hypothesis attributing arrhythmia in Brugada Syndrome to right ventricular (RV)
outflow tract (RVOT) conduction abnormalities arising from Nav1. 5 insufficiency and fibrotic …

[HTML][HTML] Effects of pharmacological gap junction and sodium channel blockade on S1S2 restitution properties in Langendorff-perfused mouse hearts

G Tse, T Liu, G Li, W Keung, JM Yeo, YWF Chan… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Gap junctions and sodium channels are the major molecular determinants of normal and
abnormal electrical conduction through the myocardium, however, their exact contributions …

Mechanisms of ventricular arrhythmogenesis in the age dependent Pgc-1β-/-model of mitochondrial dysfunction.

S Ahmad - 2019 - repository.cam.ac.uk
Sudden cardiac death is a leading cause of mortality worldwide. Ventricular arrhythmias,
both ventricular tachycardia and ventricular fibrillation, are the primary arrhythmias that lead …

Tools of our trade.

A Bondke Persson, PB Persson - Acta Physiologica, 2013 - search.ebscohost.com
Tools of our trade Page 1 ExActa Tools of our trade The compartmentalization of living cells
and the generation of chemical and electrical gradients are a prerequisite for life as we know it …