This Perspective focuses on thiol-mediated uptake, that is, the entry of substrates into cells
enabled by oligochalcogenides or mimics, often disulfides, and inhibited by thiol-reactive …

Given their potential in a better characterization and diagnosis of major pathologies like
cancer or chronic inflammation, redox-activated Magnetic Resonance Imaging (MRI) probes …

Here we report a simple Mn coordination complex with utility as a redox-sensitive MR probe.
The HBET ligand stabilizes both the Mn2+ and Mn3+ oxidation states. In the presence of …

Immune stimulating agents like Toll-like receptor 7 (TLR7) agonists induce potent antitumor
immunity but are limited in their therapeutic window due to off-target immune activation …

The reduction/oxidation (redox) potential of tissue is tightly regulated in order to maintain
normal physiological processes, but is disrupted in disease states. Thus, the development of …

The development of responsive or “smart” magnetic resonance imaging (MRI) contrast
agents that can report specific biomarker or biological events has been the focus of MRI …

Lanthanides complexes are indispensable in fields related to medicine and biology. Their
success lies in the great number of unpaired electrons (4f 7 configuration of the Gd 3+ ion) …

We report the development, as well as the in vitro and in vivo testing, of a sprayable
nanotherapeutic that uses surface engineered custom-designed multiarmed peptide grafted …

Controlled self-assembly of small molecule gadolinium (Gd) complexes into nanoparticles
(GdNPs) is emerging as an effective approach to design activatable magnetic resonance …

Cell tracking by magnetic resonance imaging (MRI) is an emerging technique that typically
requires the use of MRI contrast agents (CAs). A MRI CA for cellular imaging should label …