Coenzyme Q10 Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases

FM Gutierrez-Mariscal, AP Arenas-de Larriva… - International journal of …, 2020 - mdpi.com
Apart from its main function in the mitochondria as a key element in electron transport,
Coenzyme Q10 (CoQ10) has been described as having multiple functions, such as oxidant …

Role of Coenzyme Q10 in Health and Disease: An Update on the Last 10 Years (2010–2020)

I Cirilli, E Damiani, PV Dludla, I Hargreaves… - Antioxidants, 2021 - mdpi.com
The present review focuses on preclinical and clinical studies conducted in the last decade
that contribute to increasing knowledge on Coenzyme Q10's role in health and disease …

Canagliflozin attenuates isoprenaline-induced cardiac oxidative stress by stimulating multiple antioxidant and anti-inflammatory signaling pathways

R Hasan, S Lasker, A Hasan, F Zerin, M Zamila… - Scientific reports, 2020 - nature.com
The antidiabetic drug canagliflozin is reported to possess several cardioprotective effects.
However, no studies have investigated protective effects of canagliflozin in isoprenaline …

Canagliflozin ameliorates renal oxidative stress and inflammation by stimulating AMPK–Akt–eNOS pathway in the isoprenaline-induced oxidative stress model

R Hasan, S Lasker, A Hasan, F Zerin, M Zamila… - Scientific Reports, 2020 - nature.com
Diabetes is a leading cause of chronic kidney disease, and the high prevalence of
sympathetic nervous system (SNS) hyperactivity in diabetic patients makes them further …

[HTML][HTML] Coenzyme Q10: Clinical applications in cardiovascular diseases

A Martelli, L Testai, A Colletti, AFG Cicero - Antioxidants, 2020 - mdpi.com
Coenzyme Q 10 (CoQ 10) is a ubiquitous factor present in cell membranes and
mitochondria, both in its reduced (ubiquinol) and oxidized (ubiquinone) forms. Its levels are …

Potential health benefits of anthocyanins in oxidative stress related disorders

MA Alam, P Islam, N Subhan, MM Rahman… - Phytochemistry …, 2021 - Springer
Anthocyanins are naturally occurring water-soluble plant pigments belonging to the
flavonoids chemical class. The red, blue and purple colours of leaves, flowers and fruits of …

Coenzyme Q10 and Cardiovascular Diseases

FM Gutierrez-Mariscal, S de la Cruz-Ares… - Antioxidants, 2021 - mdpi.com
Coenzyme Q10 (CoQ10), which plays a key role in the electron transport chain by providing
an adequate, efficient supply of energy, has another relevant function as an antioxidant …

[HTML][HTML] Coenzyme Q10 supplementation mitigates piroxicam-induced oxidative injury and apoptotic pathways in the stomach, liver, and kidney

A Abdeen, A Abdelkader, D Elgazzar… - Biomedicine & …, 2020 - Elsevier
Piroxicam (PM) is an oxicam-NSAID commonly recommended for various pain and
associated inflammatory disorders. However, it is reported to have a gastric and hepato …

Quercetin prevents isoprenaline-induced myocardial fibrosis by promoting autophagy via regulating miR-223-3p/FOXO3

J Hu, X Wang, X Cui, W Kuang, D Li, J Wang - Cell Cycle, 2021 - Taylor & Francis
Atrial fibrillation (AF) is the common arrhythmias. Myocardial fibrosis (MF) is closely related
to atrial remodeling and leads to AF. MF is the main cause of cardiovascular diseases and a …

Coenzyme Q10 protects hepatocytes from ischemia reperfusion-induced apoptosis and oxidative stress via regulation of Bax/Bcl-2/PUMA and Nrf-2/FOXO-3/Sirt-1 …

AR Mahmoud, FEM Ali, TH Abd-Elhamid… - Tissue and Cell, 2019 - Elsevier
Abstract Coenzyme Q 10 (CoQ 10) is a component of the mitochondrial electron transport
chain and regarded as a strong anti-oxidant agent. In this study, we focused on the …