Direct oral anticoagulants (DOACs) are a more manageable alternative than vitamin K
antagonists (VKAs) to prevent stroke in patients with nonvalvular atrial fibrillation and to …

Dabigatran, rivaroxaban, apixaban, and edoxaban are direct oral anticoagulants (DOACs)
that are increasingly used worldwide. Taking into account their widespread use for the …

Results Median (interquartile range) age was 69 (60–76) years old; 55% had eGFR≥ 30
ml/min per 1.73 m 2, and 45% had eGFR< 30 ml/min per 1.73 m 2. Participants were …

Abstract Background Direct oral anticoagulants (DOACs) do not require concentration
monitoring. However, whether DOAC concentrations are stable and their variation between …

Background Warfarin use can trigger the occurrence of bleeding independently or as a
result of a drug–drug interaction when used in combination with nonsteroidal anti …

Background The concurrent administration of dronedarone and oral anti-coagulants is
common because both are used in managing atrial fibrillation (AF). Dronedarone is a …

abstract The class of new oral anticoagulants (NOACs) has been developed to provide
reliable oral anticoagulation without the need for therapeutic drug monitoring. Based on …

Rationale & Objective Adverse drug reactions (ADRs) are common in patients with chronic
kidney disease (CKD). The impact of kidney function decline on serious ADR risk has been …

Background Patients with atrial fibrillation are frequently nonadherent to oral anticoagulants
(OACs) prescribed for stroke and systemic embolism (SSE) prevention. We quantified the …

Direct oral anticoagulants have been an increasingly used class of drugs in the setting of
nonvalvular atrial fibrillation, defying vitamin K antagonists' monopoly when it comes to …