Procalcitonin: where are we now?

B Hamade, DT Huang - Critical Care Clinics, 2020 - criticalcare.theclinics.com
Procalcitonin (PCT) is a protein that consists of 116 amino acids and is the peptide precursor
of calcitonin. Calcitonin is initially biosynthesized as PCT, which, under normal conditions, is …

Consideration of a new definition of clinically relevant myocardial infarction after coronary revascularization: an expert consensus document from the Society for …

ID Moussa, LW Klein, B Shah, R Mehran… - Journal of the American …, 2013 - jacc.org
Numerous definitions have been proposed for the diagnosis of myocardial infarction (MI)
after coronary revascularization. The universal definition for MI designates post procedural …

Analytical characteristics of high-sensitivity cardiac troponin assays

FS Apple, PO Collinson… - Clinical …, 2012 - academic.oup.com
Abstract BACKGROUND Cardiac troponins I (cTnI) and T (cTnT) have received international
endorsement as the standard biomarkers for detection of myocardial injury, for risk …

Cardiac troponins: contemporary biological data and new methods of determination

A Chaulin - Vascular health and risk management, 2021 - Taylor & Francis
Laboratory diagnosis plays one of the key roles in the diagnosis of many diseases, including
cardiovascular diseases (CVD). The methods underlying the in vitro study of many CVD …

Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes

EM Antman, MJ Tanasijevic, B Thompson… - … England Journal of …, 1996 - Mass Medical Soc
Background In patients with acute coronary syndromes, it is desirable to identify a sensitive
serum marker that is closely related to the degree of myocardial damage, provides …

Troponin: the biomarker of choice for the detection of cardiac injury

L Babuin, AS Jaffe - Cmaj, 2005 - Can Med Assoc
It has been known for 50 years that transaminase activity increases in patients with acute
myocardial infarction. With the development of creatine kinase (CK), biomarkers of cardiac …

Troponin elevation in heart failure: prevalence, mechanisms, and clinical implications

RD Kociol, PS Pang, M Gheorghiade… - Journal of the American …, 2010 - jacc.org
Circulating biomarkers have become increasingly important in diagnosing and risk
stratifying patients with heart failure (HF). While the natriuretic peptides have received much …

High-sensitivity assays for troponin in patients with cardiac disease

D Westermann, JT Neumann, NA Sörensen… - Nature Reviews …, 2017 - nature.com
Troponin is a widely used biomarker in patients with cardiac disease. The use of troponin is
well established in patients with suspected acute myocardial infarction (AMI), but troponin …

Elevations of cardiac troponin I associated with myocarditis: experimental and clinical correlates

SC Smith, JH Ladenson, JW Mason, AS Jaffe - Circulation, 1997 - Am Heart Assoc
Background Endomyocardial biopsy is currently the standard method used to diagnose
myocarditis. However, it is invasive and has a low diagnostic yield. Because the histological …

Biochemical markers of myocardial injury. Is MB creatine kinase the choice for the 1990s?

JE Adams 3rd, DR Abendschein, AS Jaffe - Circulation, 1993 - Am Heart Assoc
M odern medical practice requires rapid decisions. Patients must be triaged faster, treated
more expeditiously, and discharged earlier. Diagnostic tests used to evaluate patients with …