Gene copy-number differences due to gene duplications and deletions are rampant in
natural populations and play a crucial role in the evolution of genome complexity. Per-locus …

Knowledge of mutation processes is central to understanding virtually all evolutionary
phenomena and the underlying nature of genetic disorders and cancers. However, the …

Gene and genome duplications are the primary source of new genes and novel functions
and have played a pivotal role in the evolution of genomic and organismal complexity [1, 2] …

A century of genetic analysis has revealed that multiple mechanisms control the distribution
of meiotic crossover events. In Drosophila melanogaster, two significant positional controls …

Males and females share most of the same genes, so selection in one sex will typically
produce a correlated response in the other sex. Yet, the sexes have evolved to differ in a …

Genetically modified conditional lethal strains have been created to improve the control of
insect pest populations damaging to human health and agriculture. However, understanding …

The origin and maintenance of sex remains one of the most debated topics in evolutionary
biology. Investigations of the molecular genetic consequences of asexuality, such as direct …

Segmental duplications are enriched within many eukaryote genomes, and their potential
consequence is gene duplication. While previous theoretical studies of gene duplication …

Y and W chromosomes often stop recombining and degenerate. Most work on
recombination suppression has focused on the mechanisms favoring recombination arrest …

In the classic view introduced by RA Fisher, a quantitative trait is encoded by many loci with
small, additive effects. Recent advances in quantitative trait loci mapping have begun to …