Pull the plug: anti‐angiogenesis potential of natural products in gastrointestinal cancer therapy

Y Ai, Z Zhao, H Wang, X Zhang, W Qin… - Phytotherapy …, 2022 - Wiley Online Library
Gastrointestinal cancer (GIC), including gastric cancer and colorectal cancer, is a common
malignant tumor originating from the gastrointestinal epithelium. Although the pathogenesis …

Therapeutic effect of natural polyphenols against glioblastoma

O Beylerli, A Beilerli, A Shumadalova… - Frontiers in Cell and …, 2022 - frontiersin.org
Glioblastoma (GBM) is the most common and aggressive tumor of the central nervous
system, which has a highly invasive growth pattern, which creates poor prospects for patient …

Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays

Y Gupta, D Maciorowski, SE Zak, KA Jones… - Methods, 2021 - Elsevier
Abstract SARS-CoV-2, the virus that causes COVID-19 consists of several enzymes with
essential functions within its proteome. Here, we focused on repurposing approved and …

The flavonol isoquercitrin promotes mitochondrial-dependent apoptosis in SK-Mel-2 melanoma cell via the PI3K/AKT/mTOR pathway

YS Won, JH Kim, RCM Lizardo, HJ Min, HD Cho… - Nutrients, 2020 - mdpi.com
Isoquercitrin (IQ), a major flavonol present in Prunus mume fruit, has gained much attention
in recent studies because of its superior bioavailability and physiological effects. In this …

Anticancer activities of phytoconstituents and their liposomal targeting strategies against tumor cells and the microenvironment

J Zhang, X Li, L Huang - Advanced drug delivery reviews, 2020 - Elsevier
Various bioactive ingredients have been extracted from Chinese herbal medicines (CHMs)
that affect tumor progression and metastasis. To further understand the mechanisms of …

Phytochemical Profile and Biological Activities of Tendrils and Leaves Extracts from a Variety of Vitis vinifera L.

ML Moldovan, R Carpa, I Fizeșan, L Vlase, C Bogdan… - Antioxidants, 2020 - mdpi.com
Winery industry by-products have a great reuse potential in the pharmaceutical and
cosmetic fields due to their bioactive compounds. This study investigates the phytochemical …

Beyond Traditional Use of Alchemilla vulgaris: Genoprotective and Antitumor Activity In Vitro

S Jelača, Z Dajić-Stevanović, N Vuković, S Kolašinac… - Molecules, 2022 - mdpi.com
Alchemilla vulgaris L.(lady's mantle) was used for centuries in Europe and Balkan countries
for treatments of numerous conditions and diseases of the reproductive system, yet some of …

Halophytic grasses, a new source of nutraceuticals? A review on their secondary metabolites and biological activities

MV Faustino, MAF Faustino, DCGA Pinto - International Journal of …, 2019 - mdpi.com
The Poaceae family, known as grasses, is distributed worldwide and is considered the most
important group of monocotyledonous crops. Salt stress is multifactorial, therefore to survive …

[HTML][HTML] Potential of terpenoids and flavonoids from Asteraceae as anti-inflammatory, antitumor, and antiparasitic agents

VP Sülsen, E Lizarraga, NZ Mamadalieva… - Evidence-based …, 2017 - ncbi.nlm.nih.gov
Asteraceae (formerly known as Compositae) is one of the largest families of higher plants,
with more than 1700 genera and approximately 24000 species, which grow in varied …

Phytochemical analysis and biological evaluation of Ferulago setifolia K. Koch

S Gözcü, Z Akşit, S Şimşek, A Kandemir… - Journal of the …, 2024 - Wiley Online Library
Abstract BACKGROUND Ferulago setifolia K. Koch (Apiaceae) has been the subject of this
study, aiming to comprehensively determine its phenolic fingerprint and evaluate its various …