The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

In the decade since oral rotavirus vaccines (ORV) were recommended by the World Health
Organization for universal inclusion in all national immunization programs, significant yet …

Background Rotavirus is a common cause of diarrhoea, diarrhoea‐related hospital
admissions, and diarrhoea‐related deaths worldwide. Rotavirus vaccines prequalified by …

Background A head-to-head comparison of the most widely used oral rotavirus vaccines has
not previously been done, particularly in a high child mortality setting. We therefore aimed to …

Rotavirus is a major cause of severe pediatric diarrhea worldwide. In 2006, 2 live, oral
rotavirus vaccines, Rotarix and RotaTeq, were licensed for use in infants and were rapidly …

Acute respiratory infections (ARIs) are one of the most common causes of morbidity and
mortality in young children. The aim of our study was to examine whether variation in …

In 2020, with the advent of a pandemic touching all aspects of global life, there is a renewed
interest in nutrition solutions to support the immune system. Infants are vulnerable to …

Histo-blood group antigens, which are present on gut epithelial surfaces, function as
receptors or attachment factors and mediate susceptibility to rotavirus infection. The major …

Background Rotavirus is a leading cause of severe pediatric gastroenteritis; 2 highly
effective vaccines are used in the United States (US). We aimed to identify correlates of …

Background Histo-blood group antigens (HBGAs) may influence immune responses to
rotavirus vaccination. Methods HBGA phenotyping was determined by detection of antigens …