Amino acid fermentation is one of the major pillars of industrial biotechnology. The multi-
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …

Genome editing in bacteria encompasses a wide array of laborious and multi-step methods
such as suicide plasmids. The discovery and applications of clustered regularly interspaced …

Abstract Development of hyperproducing strains is important for biomanufacturing of
biochemicals and biofuels but requires extensive efforts to engineer cellular metabolism and …

Microbial cell factories (MCFs) convert low-cost carbon sources into valuable compounds.
The CRISPR/Cas9 system has revolutionized MCF construction as a remarkable genome …

CRISPR-Cas technologies have greatly reshaped the biology field. In this review, we
discuss the CRISPR-Cas with a particular focus on the associated technologies and …

CRISPR/Cas9 technology has become the most examined gene editing technology in
recent years due to its simple design, yet low cost, high efficiency, and simple operation …

Biology produces a universe of chemicals whose precision and complexity is the envy of
chemists. Over the last 30 years, the expansive field of metabolic engineering has many …

Production of food-related products using microorganisms in an environmentally friendly
manner is a crucial solution to global food safety and environmental pollution issues …

The clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas)
system has been rapidly developed as versatile genomic engineering tools with high …

Rhodococcus spp. are organic solvent-tolerant strains with strong adaptive abilities and
diverse metabolic activities, and are therefore widely utilized in bioconversion, biosynthesis …