Cannabis use and cannabis use disorder
Cannabis use disorder (CUD) is an underappreciated risk of using cannabis that affects~
10% of the 193 million cannabis users worldwide. The individual and public health burdens …
10% of the 193 million cannabis users worldwide. The individual and public health burdens …
US epidemiology of cannabis use and associated problems
DS Hasin - Neuropsychopharmacology, 2018 - nature.com
This review provides an overview of the changing US epidemiology of cannabis use and
associated problems. Adults and adolescents increasingly view cannabis as harmless, and …
associated problems. Adults and adolescents increasingly view cannabis as harmless, and …
DSM-5 criteria for substance use disorders: recommendations and rationale
DS Hasin, CP O'brien, M Auriacombe… - American Journal of …, 2013 - Am Psychiatric Assoc
Since DSM-IV was published in 1994, its approach to substance use disorders has come
under scrutiny. Strengths were identified (notably, reliability and validity of dependence), but …
under scrutiny. Strengths were identified (notably, reliability and validity of dependence), but …
Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects
EB Russo - British journal of pharmacology, 2011 - Wiley Online Library
Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964,
when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic …
when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic …
Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review
Sleep abnormalities are associated with acute and chronic use of addictive substances.
Although sleep complaints associated with use and abstinence from addictive substances …
Although sleep complaints associated with use and abstinence from addictive substances …
Substance abuse in women
Gender differences in rates of substance abuse have been consistently observed in the
general population and treatment-seeking samples, with men exhibiting significantly higher …
general population and treatment-seeking samples, with men exhibiting significantly higher …
Prevalence of cannabis withdrawal symptoms among people with regular or dependent use of cannabinoids: a systematic review and meta-analysis
Importance Cannabis withdrawal syndrome (CWS)—a diagnostic indicator of cannabis use
disorder—commonly occurs on cessation of heavy and prolonged cannabis use. To date …
disorder—commonly occurs on cessation of heavy and prolonged cannabis use. To date …
Cannabis and anxiety: a critical review of the evidence
Background Anxiety reactions and panic attacks are the acute symptoms most frequently
associated with cannabis use. Understanding the relationship between cannabis and …
associated with cannabis use. Understanding the relationship between cannabis and …
Efficacy and safety of a fatty acid amide hydrolase inhibitor (PF-04457845) in the treatment of cannabis withdrawal and dependence in men: a double-blind, placebo …
DC D'Souza, J Cortes-Briones, G Creatura… - The Lancet …, 2019 - thelancet.com
Background Cannabis is one of the most widely used drugs worldwide. Cannabis use
disorder is characterised by recurrent use of cannabis that causes significant clinical and …
disorder is characterised by recurrent use of cannabis that causes significant clinical and …
Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials
M Haney, M Vallée, S Fabre, S Collins Reed… - Nature Medicine, 2023 - nature.com
Cannabis use disorder (CUD) is widespread, and there is no pharmacotherapy to facilitate
its treatment. AEF0117, the first of a new pharmacological class, is a signaling-specific …
its treatment. AEF0117, the first of a new pharmacological class, is a signaling-specific …