Inhibitors of the Sec61 complex and novel high throughput screening strategies to target the protein translocation pathway
E Pauwels, R Schülein, K Vermeire - International journal of molecular …, 2021 - mdpi.com
Proteins targeted to the secretory pathway start their intracellular journey by being
transported across biological membranes such as the endoplasmic reticulum (ER). A central …
transported across biological membranes such as the endoplasmic reticulum (ER). A central …
The stress of lung aging: Endoplasmic reticulum and senescence Tete-a-Tete
Beyond the structural changes, features including the dysregulation of endoplasmic
reticulum (ER) stress response and increased senescence characterize the lung aging. ER …
reticulum (ER) stress response and increased senescence characterize the lung aging. ER …
Nano fraction of pesticide induces genotoxicity and oxidative stress‐dependent reticulum stress
C Paz‐Trejo, F Arenas‐Huertero… - Environmental …, 2024 - Wiley Online Library
The implementation of nanotechnology in different sectors has generated expectations as a
new source of use due to the novel characteristics that it will bring. Particularly, nano …
new source of use due to the novel characteristics that it will bring. Particularly, nano …
Effect of temperature and nucleotide on the binding of BiP chaperone to a protein substrate
BiP (immunoglobulin heavy‐chain binding protein) is a Hsp70 monomeric ATPase motor
that plays broad and crucial roles in maintaining proteostasis inside the cell. Structurally, BiP …
that plays broad and crucial roles in maintaining proteostasis inside the cell. Structurally, BiP …
Characterization of the interaction between the Sec61 translocon complex and ppαF using optical tweezers
L Robeson, N Casanova‐Morales… - Protein …, 2024 - Wiley Online Library
The Sec61 translocon allows the translocation of secretory preproteins from the cytosol to
the endoplasmic reticulum lumen during polypeptide biosynthesis. These proteins possess …
the endoplasmic reticulum lumen during polypeptide biosynthesis. These proteins possess …
Towards the understanding of molecular motors and its relationship with local unfolding
Z Alavi, N Casanova-Morales… - Quarterly Reviews of …, 2024 - cambridge.org
Molecular motors are machines essential for life since they convert chemical energy into
mechanical work. However, the precise mechanism by which nucleotide binding, catalysis …
mechanical work. However, the precise mechanism by which nucleotide binding, catalysis …
Estudio de las propiedades funcionales y estructurales de la proteína de estrés térmico BiP (Proteína de Unión a Inmunoglobulina): un regulador maestro con …
MI Lagos Espinoza - 2023 - repositorio.uchile.cl
BiP es una chaperona perteneciente a la familia Hsp70 (Heat shock protein 70) que está
involucrada en la regulación de importantes procesos biológicos como la síntesis …
involucrada en la regulación de importantes procesos biológicos como la síntesis …
[PDF][PDF] Régulation de l'expression des récepteurs couplés aux protéines G par le complexe de chaperonines cytosoliques et localisation/fonction mitochondriale du …
S Genier - 2021 - savoirs.usherbrooke.ca
Thèse présentée à la Faculté de médecine et des sciences de la santé en vue de l'obtention
du diplôme de philosophiae doctor (Ph. D.) en Pharmacologie, Faculté de médecine et des …
du diplôme de philosophiae doctor (Ph. D.) en Pharmacologie, Faculté de médecine et des …