Phagocytosis, the regulated uptake of large particles (> 0.5 μm in diameter), is essential for
tissue homeostasis and is also an early, critical component of the innate immune response …

Phagocytosis is a specialized process that enables cellular ingestion and clearance of
microbes, dead cells and tissue debris that are too large for other endocytic routes. As such …

CD47 acts as a" don't eat me" signal that protects cells from phagocytosis by binding and
activating its receptor SIPRA on macrophages. CD47 suppresses multiple different pro …

Atherosclerosis, the primary cause of cardiovascular disease (CVD), is a chronic
inflammatory disorder in the walls of medium and large arteries. CVD is currently …

Targeting a specific chemokine/receptor axis in atherosclerosis remains challenging.
Soluble receptor-based strategies are not established for chemokine receptors due to their …

Macrophages respond to several stimuli by forming florid membrane ruffles that lead to fluid
uptake by macropinocytosis. This type of induced macropinocytosis, executed by a variety of …

We have previously reported the in vitro hypocholesterolemic, anti-inflammatory, and
antioxidant effects of Alcalase-generated lupin protein hydrolysate (LPH). Given that …

Atherosclerosis can be regarded as a chronic disease derived from the interaction between
disordered lipoproteins and an unsuitable immune response. The evolution of foam cells is …

Phagocytes recognize and eliminate pathogens, alert other tissues of impending threats,
and provide a link between innate and adaptive immunity. They also maintain tissue …

Abstract miR-758-3p plays an important role via regulting ABCA1-mediated cholesterol
efflux in atherosclerosis. However, the mechanism of miR-758-5p in cholesterol metabolism …