The accumulation of an excessive amount of body fat can cause type 2 diabetes, and the
risk of type 2 diabetes increases linearly with an increase in body mass index. Accordingly …

Initial studies found increased severity of coronavirus disease 2019 (COVID-19), caused by
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients …

The 1921 discovery of insulin was a Big Bang from which a vast and expanding universe of
research into insulin action and resistance has issued. In the intervening century, some …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated
symptoms, named coronavirus disease 2019 (COVID-19), have rapidly spread worldwide …

Metabolic flexibility is the ability to respond or adapt to conditional changes in metabolic
demand. This broad concept has been propagated to explain insulin resistance and …

Type 2 diabetes mellitus (T2DM) is an expanding global health problem, closely linked to
the epidemic of obesity. Individuals with T2DM are at high risk for both microvascular …

The article discusses how to measure insulin resistance in muscle, liver, and adipose tissue
in human participants. The most frequently used methodologies to evaluate insulin …

The prevalence of sarcopenic obesity is increasing worldwide, particularly amongst aging
populations. Insulin resistance is the core mechanism of sarcopenic obesity and is also …

Glucose levels in blood must be constantly maintained within a tight physiological range to
sustain anabolism. Insulin regulates glucose homeostasis via its effects on glucose …

OBJECTIVE Sodium–glucose cotransporter 2 (SGLT-2) inhibitors are the most recently
approved antihyperglycemic medications. We sought to describe their association with …