Statistical methods and resources for biomarker discovery using metabolomics
Metabolomics is a dynamic tool for elucidating biochemical changes in human health and
disease. Metabolic profiles provide a close insight into physiological states and are highly …
disease. Metabolic profiles provide a close insight into physiological states and are highly …
Untargeted metabolomics of COVID-19 patient serum reveals potential prognostic markers of both severity and outcome
Introduction The diagnosis of COVID-19 is normally based on the qualitative detection of
viral nucleic acid sequences. Properties of the host response are not measured but are key …
viral nucleic acid sequences. Properties of the host response are not measured but are key …
The plasma metabolome of long COVID patients two years after infection
Y López-Hernández, J Monárrez-Espino, DAG López… - Scientific reports, 2023 - nature.com
One of the major challenges currently faced by global health systems is the prolonged
COVID-19 syndrome (also known as “long COVID”) which has emerged as a consequence …
COVID-19 syndrome (also known as “long COVID”) which has emerged as a consequence …
Profiling metabolites and lipoproteins in COMETA, an Italian cohort of COVID-19 patients
Metabolomics and lipidomics have been used in several studies to define the biochemical
alterations induced by COVID-19 in comparison with healthy controls. Those studies …
alterations induced by COVID-19 in comparison with healthy controls. Those studies …
Gut microbiome modified by bariatric surgery improves insulin sensitivity and correlates with increased brown fat activity and energy expenditure
J Yadav, T Liang, T Qin, N Nathan, KJP Schwenger… - Cell Reports …, 2023 - cell.com
Alterations in the microbiome correlate with improved metabolism in patients following
bariatric surgery. While fecal microbiota transplantation (FMT) from obese patients into germ …
bariatric surgery. While fecal microbiota transplantation (FMT) from obese patients into germ …
Saliva metabolomic profile of COVID-19 patients associates with disease severity
N Saheb Sharif-Askari, NC Soares, HA Mohamed… - Metabolomics, 2022 - Springer
Abstract Introduction Coronavirus disease 2019 (COVID-19) is strongly linked to
dysregulation of various molecular, cellular, and physiological processes that change …
dysregulation of various molecular, cellular, and physiological processes that change …
Integrative plasma metabolic and lipidomic modelling of SARS-CoV-2 infection in relation to clinical severity and early mortality prediction
An integrative multi-modal metabolic phenotyping model was developed to assess the
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19
C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in Molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …
An integrated analysis and comparison of serum, saliva and sebum for COVID-19 metabolomics
The majority of metabolomics studies to date have utilised blood serum or plasma, biofluids
that do not necessarily address the full range of patient pathologies. Here, correlations …
that do not necessarily address the full range of patient pathologies. Here, correlations …