Children and adolescents with cancer often undergo intensive chemotherapy treatment to
obtain remission and long-term survival. The pursuit of successful treatment outcomes may …

Children and adolescents receiving treatment for cancer experience multiple symptoms as a
consequence of their disease and its treatment that interfere with the child's quality of life …

We know little about the safety or efficacy of pharmacological medicines for children and
adolescents with chronic pain, despite their common use. Our aim was to conduct an …

Children with acute lymphoblastic leukemia (ALL) undergo intense anticancer treatment. We
systematically reviewed 22 studies evaluating 2,073 ALL patients' health‐related quality of …

Pain, anxiety, or depression are very prevalent in children and adolescents with cancer,
which is a great challenge for health professionals. Several studies pointing out the positive …

Problem Leukemia is the most common form of childhood cancer worldwide. Children living
with leukemia experience various problems because of the disease's progression, harmful …

Context Cancer treatment symptoms play a major role in determining the health of children
with cancer. Symptom toxicity often results in complications, treatment delays, and therapy …

Background Children with cancer receiving chemotherapy commonly report a cluster of
psychoneurological symptoms (PNS), including pain, fatigue, anxiety, depression, and …

This review describes the pivotal roles of cell-cycle and checkpoint regulators and discusses
development of specific cell-cycle inhibitors for therapeutic use for pediatric cancer. The …

Simple Summary Sleep problems are faced by many children with cancer, and they can lead
to negative physical and psychological outcomes, as well as to a lower quality of life …