Fluorescence microscopy—an outline of hardware, biological handling, and fluorophore considerations

SM Hickey, B Ung, C Bader, R Brooks, J Lazniewska… - Cells, 2021 - mdpi.com
Fluorescence microscopy has become a critical tool for researchers to understand biological
processes at the cellular level. Micrographs from fixed and live-cell imaging procedures …

A new twist on PIFE: photoisomerisation-related fluorescence enhancement

E Ploetz, B Ambrose, A Barth, R Börner… - … and applications in …, 2023 - iopscience.iop.org
PIFE was first used as an acronym for protein-induced fluorescence enhancement, which
refers to the increase in fluorescence observed upon the interaction of a fluorophore, such …

Molecular imprinted nanoparticle assisted surface plasmon resonance biosensors for detection of thrombin

D Ҫimen, N Bereli, S Günaydın, A Denizli - Talanta, 2022 - Elsevier
In this study, we designed a surface plasmon resonance (SPR) biosensors based on
molecular imprinting to detect low amounts of thrombin directly in a short time, both in …

A “signal-on” chemiluminescence biosensor for thrombin detection based on DNA functionalized magnetic sodium alginate hydrogel and metalloporphyrinic metal …

Y Lin, Y Sun, Y Dai, W Sun, X Zhu, H Liu, R Han, D Gao… - Talanta, 2020 - Elsevier
A “signal-on” chemiluminescence biosensor was established for detecting thrombin. The
thrombin aptamer1-functionalized magnetic sodium alginate (Malg-Apt1) hydrogel was …

CRISPR/Cas12a-regulated homogeneous electrochemical aptasensor for amplified detection of protein

M Qing, Z Sun, L Wang, SZ Du, J Zhou, Q Tang… - Sensors and Actuators B …, 2021 - Elsevier
Electrochemical aptasensors have been wildly used in the detection and quantification of
protein biomarkers, but their practical applications are limited by inefficient signal …

Aptamer-based solution-gated graphene transistors for highly sensitive and real-time detection of thrombin molecules

H Yu, Z Zhao, B Xiao, M Deng, Z Wang, Z Li… - Analytical …, 2021 - ACS Publications
Thrombin is an important biomarker for various diseases and biochemical reactions. Rapid
and real-time detection of thrombin that quickly neutralizes in early coagulation in the body …

Ultrasensitive determination of thrombin by using an electrode modified with WSe2 and gold nanoparticles, aptamer-thrombin-aptamer sandwiching, redox cycling …

YH Wang, H Xia, KJ Huang, X Wu, YY Ma, R Deng… - Microchimica Acta, 2018 - Springer
A sensitive aptamer/protein binding-triggered sandwich assay for thrombin is described. It is
based on electrochemical-chemical-chemical redox cycling using a glassy carbon electrode …

Binding-induced 3D-bipedal DNA walker for cascade signal amplification detection of thrombin combined with catalytic hairpin assembly strategy

E Xiong, D Zhen, L Jiang, X Zhou - Analytical chemistry, 2019 - ACS Publications
As an important biomarker, thrombin (TB) is a major player in thrombosis and hemostasis
and has attracted increasing attention involving its determination. Herein a universal and …

[HTML][HTML] Highly sensitive quantification of Alzheimer's disease biomarkers by aptamer-assisted amplification

HN Chan, D Xu, SL Ho, D He, MS Wong, HW Li - Theranostics, 2019 - ncbi.nlm.nih.gov
Abstract Alzheimer's disease (AD), a chronic neurodegenerative disease associated with the
loss of neurons in the brain, is the most pervasive type of dementia; 47 million people are …

Methylene blue-encapsulated Cu (I)/(Ⅱ) mixed-valence MOF with spontaneously recycled catalysis for electrochemical-colorimetric dual-signal readout aptasensor

H Yu, G Xu, L Li, H Peng, H Chang, Z Chen, H Fu… - Microchemical …, 2024 - Elsevier
The sensitive and accurate detection of thrombin (Tb) is of significance for early diagnosis of
thrombosis, vascular injuries, and cancers. A dual-signal aptasensor with effective signal …