Dietary aflatoxin B1 and antimalarial—a lumefantrine/artesunate—therapy perturbs male rat reproductive function via pro-inflammatory and oxidative mechanisms

SE Owumi, AO Umez, U Arunsi, CE Irozuru - Scientific Reports, 2023 - nature.com
We investigated the impact of Coartem™(COA) and aflatoxin B1 (AFB1) on rats'
hypothalamus, epididymis, and testis. Male rats were randomly grouped (n= 5 rats) and …

[HTML][HTML] Evaluation of rational prescribing in a hospital paediatric outpatient clinic in Nigeria

BI Okoye, JC Udemba, CA Ndugba… - BMJ paediatrics …, 2022 - ncbi.nlm.nih.gov
Background Irrational prescribing is a continuing public health issue in low/middle-income
countries. This study evaluated the drug use pattern of medicines in paediatrics aged below …

Malaria Frontline Project: strategic approaches to improve malaria control program leveraging experiences from Kano and Zamfara States, Nigeria, 2016–2019

A Adewole, O Ajumobi, N Waziri, AA Umar… - BMC Health Services …, 2023 - Springer
Abstract Background The Malaria Frontline Project (MFP) supported the National Malaria
Elimination Program for effective program implementation in the high malaria-burden states …

Health workers' perception of malaria rapid diagnostic test and factors influencing compliance with test results in Ebonyi state, Nigeria

IF Obi, K Sabitu, A Olorukooba, AS Adebowale… - PLoS …, 2019 - journals.plos.org
Background The standard practice in treating uncomplicated malaria is to prescribe
artemisinin-based combination therapy (ACT) for only patients with positive test results …

[PDF][PDF] Perceptions and attitudes to health-seeking delays for malaria treatment in Makurdi, Nigeria

PA Ochepo - 2022 - uobrep.openrepository.com
Background Global research on health-seeking behaviours for malaria treatment suggests
that exploring community perceptions and attitudes to health-seeking is essential in …

Malaria Diagnosis at the Pediatric Emergency Unit of a Teaching Hospital in Makurdi, North Central Nigeria

A Michael, NB Samba, MG Adikwu, MO Ochoga… - Ethiopian Journal of …, 2024 - ajol.info
BACKGROUND: Globally, there were 241 million cases of malaria in 2020, with an
estimated 627,000 deaths with Nigeria accounting for 27% of the global malaria cases. In …

Artemisinin-based antimalarial combination therapy amongst healthcare professionals in a tertiary facility in south-south Nigeria: preferences, tolerability, and cost …

AS Ayinbuomwan, AO Opadeyi, AO Isah - Research Journal of Health …, 2022 - ajol.info
Background: Nigeria adopted the Artemisinin-Based Combination Therapy (ACT) as the
mainstay of treating uncomplicated malaria in February 2005. However, the individual …

[HTML][HTML] Absence of Biomakers of Resistance in K13 Propeller Gene of Plasmodium falciparum from Gombe LGA of Gombe State, Nigeria

I Muhammad, PM Sale, AL Midala - Advances, 2022 - advancesj.org
Malaria is still one of the life threatening parasitic disease in Sub-Saharan Africa. The
causative agent of the disease always provide a means of avoiding the action of most …

Artemisinin-based combination therapy amongst medical students in the University of Benin, South-South Nigeria: A cross-sectional study

S Ayinbuomwan, A Opadeyi… - Annals of Clinical and …, 2022 - africa.pagepress.net
Since 2005, the recommended first-line therapy for uncomplicated malaria in Nigeria has
been Artemisinin-based Combination Therapy (ACT). Previous research indicates that these …

[PDF][PDF] Antiplasmodial Potential of Thaumatococcus danielli Extracts (Benth.) against Plasmodium berghei Infected Mice.

MA Olasope, OT Ojuromi, O Ajibaye… - Tropical Journal of …, 2023 - researchgate.net
Malaria is still a global health issue causing high morbidity and mortality across tropical and
subtropical countries particularly sub-Saharan Africa (SSA). 1 The disease is caused by the …