Itch is a common sensory experience that is prevalent in patients with inflammatory skin
diseases, as well as in those with systemic and neuropathic conditions. In patients with …

Itch is a defining symptom of atopic dermatitis. Crosstalk between keratinocytes, the immune
system and non‐histaminergic sensory nerves is responsible for the pathophysiology of …

Atopic dermatitis (AD) is a common, chronic-relapsing inflammatory skin disease with
significant disease burden. Genetic and environmental trigger factors contribute to AD …

Atopic dermatitis (AD) is a common chronic skin disease with multiple pathogenic factors
including skin barrier dysfunction, immune abnormalities, and pruritus. This review …

Similar to chronic pain, chronic itch is frequently linked to neural sensitization, a
phenomenon wherein the nervous system becomes hypersensitive to stimuli. This process …

Background IL-36 cytokines are members of the IL-1 superfamily. Increasing evidence in the
IL-36 pathway demonstrates their potential as a therapeutic target for treating inflammatory …

Abstract Ethnopharmacological relevance A Traditional Chinese Medicine (TCM) formula
(VYAC) consists of three herbs including Viola yedoensis Makino, herb (Violaceae, Viola) …

Chronic itch is a complex psychophysiological sensation, which can severely affect the
quality of life in patients with atopic dermatitis and psoriasis. Itch depends on the irritation of …

Irritable bowel syndrome is a gastrointestinal disorder due to multiple pathologies. While
patients with this condition experience anxiety and depressed mood more frequently than …

Atopic dermatitis (AD) is a disease that can have a high impact on quality of life, especially
due to itch and skin pain. This paper utilizes expertise from members of the International …