[HTML][HTML] Small tech, big impact: Agri-nanotechnology journey to optimize crop protection and production for sustainable agriculture

A Singh, VD Rajput, A Varshney, K Ghazaryan… - Plant Stress, 2023 - Elsevier
The world's climate shifts rapidly, leading to increasingly severe and volatile weather,
negatively impacting crop yields. To produce long-lasting crops, cutting-edge …

Nanoparticle drug delivery systems for synergistic delivery of tumor therapy

D Chen, X Liu, X Lu, J Tian - Frontiers in Pharmacology, 2023 - frontiersin.org
Nanoparticle drug delivery systems have proved anti-tumor effects; however, they are not
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …

Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity

Y Zhu, J Ma, R Shen, J Lin, S Li, X Lu… - Nature biomedical …, 2023 - nature.com
Lipid nanoparticles (LNPs) can be designed to potentiate cancer immunotherapy by
promoting their uptake by antigen-presenting cells, stimulating the maturation of these cells …

Lipid nanoparticles optimized for targeting and release of nucleic acid

Y Jia, X Wang, L Li, F Li, J Zhang… - Advanced Materials, 2024 - Wiley Online Library
Lipid nanoparticles (LNPs) are currently the most promising clinical nucleic acids drug
delivery vehicles. LNPs prevent the degradation of cargo nucleic acids during blood …

Current advances in non‐viral gene delivery systems: Liposomes versus extracellular vesicles

Z Belhadj, Y Qie, RP Carney, Y Li, G Nie - BMEMat, 2023 - Wiley Online Library
In the past decade, nucleic acid‐based drugs have emerged as an extremely promising
approach for silencing specific disease‐related genes and targeting undruggable ones …

mRNA-based therapeutics in cancer treatment

H Sun, Y Zhang, G Wang, W Yang, Y Xu - Pharmaceutics, 2023 - mdpi.com
Over the past two decades, significant technological innovations have led to messenger
RNA (mRNA) becoming a promising option for developing prophylactic and therapeutic …

Analysis of PEG-lipid anchor length on lipid nanoparticle pharmacokinetics and activity in a mouse model of traumatic brain injury

LE Waggoner, KF Miyasaki, EJ Kwon - Biomaterials Science, 2023 - pubs.rsc.org
Traumatic brain injury (TBI) affects millions of people worldwide, yet there are currently no
therapeutics that address the long-term impairments that develop in a large portion of …

Theranostic Lipid Nanoparticles for Renal Cell Carcinoma

X Mao, G Wang, Z Wang, C Duan, X Wu… - Advanced …, 2023 - Wiley Online Library
Renal cell carcinoma (RCC) is a common urological malignancy and represents a leading
threat to healthcare. Recent years have seen a series of progresses in the early diagnosis …

Unleashing the potential: Designing antibody-targeted lipid nanoparticles for industrial applications with CMC considerations and clinical outlook

S Wang, H Wang, A Drabek, WS Smith… - Molecular …, 2023 - ACS Publications
Antibody-targeted lipid nanoparticles (Ab-LNPs) are rapidly gaining traction as multifaceted
platforms in precision medicine, adept at delivering a diverse array of therapeutic agents …

Genetic engineered ultrasound-triggered injectable hydrogels for promoting bone reconstruction

Z Zhao, H Ruan, A Chen, W Xiong, M Zhang, M Cai… - Research, 2023 - spj.science.org
Genetic engineering technology can achieve specific gene therapy for a variety of diseases,
but the current strategy still has some flaws, such as a complex system, single treatment, and …