During fertilization, the egg and the sperm are supposed to contribute precisely one copy of
each chromosome to the embryo. However, human eggs frequently contain an incorrect …

It is more effective to maintain good health than to regain it after losing it. This work focuses
on the biochemical defense mechanisms against free radicals and their role in building and …

Multiple changes occur across various endocrine systems as an individual ages. The
understanding of the factors that cause age-related changes and how they should be …

Aging has a major detrimental effect on the optimal function of the ovary with changes in this
organ preceding the age-related deterioration in other tissues, with the middle-aged …

Reproductive aging is characterized by a decline in oocyte quantity and quality, which is
directly associated with a decline in reproductive potential, as well as poorer reproductive …

Mitochondria are well known as 'the powerhouses of the cell'. Indeed, their major role is
cellular energy production driven by both mitochondrial and nuclear DNA. Such a feature …

Heat stress is a major threat to cattle reproduction today. It has been shown that the effect of
high temperature not only has a negative effect on the hormonal balance, but also directly …

Mitochondria play diverse roles in mammalian physiology. The architecture, activity, and
physiological functions of mitochondria in oocytes are largely different from those in somatic …

Over half a century has passed since Alexey Olovnikov's groundbreaking proposal of the
end-replication problem in 1971, laying the foundation for our understanding of telomeres …

The female reproductive system is quite sensitive to regulation, and external environmental
stimuli may cause oxidative stress which in turn may lead to accelerated aging and …