Current state of the art MRI for the longitudinal assessment of cystic fibrosis

JC Woods, JM Wild, MO Wielpütz… - Journal of Magnetic …, 2020 - Wiley Online Library
Pulmonary MRI can now provide high‐resolution images that are sensitive to early disease
and specific to inflammation in cystic fibrosis (CF) lung disease. With specificity and function …

Pulmonary functional imaging: Part 1—state-of-the-art technical and physiologic underpinnings

Y Ohno, JB Seo, G Parraga, KS Lee, WB Gefter… - Radiology, 2021 - pubs.rsna.org
Over the past few decades, pulmonary imaging technologies have advanced from chest
radiography and nuclear medicine methods to high-spatial-resolution or low-dose chest CT …

Effects of elexacaftor/tezacaftor/ivacaftor therapy on lung clearance index and magnetic resonance imaging in patients with cystic fibrosis and one or two F508del …

SY Graeber, DM Renz, M Stahl… - American journal of …, 2022 - atsjournals.org
Rationale: We recently demonstrated that triple-combination CFTR (cystic fibrosis
transmembrane conductance regulator) modulator therapy with elexacaftor/tezacaftor …

Pulmonary dysfunction after pediatric COVID-19

R Heiss, L Tan, S Schmidt, AP Regensburger, F Ewert… - Radiology, 2022 - pubs.rsna.org
Background Long COVID occurs at a lower frequency in children and adolescents than in
adults. Morphologic and free-breathing phase-resolved functional low-field-strength MRI …

Expanding applications of pulmonary MRI in the clinical evaluation of lung disorders: Fleischner Society position paper

H Hatabu, Y Ohno, WB Gefter, G Parraga, B Madore… - Radiology, 2020 - pubs.rsna.org
Pulmonary MRI provides structural and quantitative functional images of the lungs without
ionizing radiation, but it has had limited clinical use due to low signal intensity from the lung …

Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI)

DG Kiely, DL Levin, PM Hassoun, D Ivy… - Pulmonary …, 2019 - journals.sagepub.com
Pulmonary hypertension (PH) is highly heterogeneous and despite treatment advances it
remains a life-shortening condition. There have been significant advances in imaging …

Free-breathing low-field MRI of the lungs detects functional alterations associated with persistent symptoms after COVID-19 infection

S Lévy, R Heiss, R Grimm, D Grodzki… - Investigative …, 2022 - journals.lww.com
Objectives With the COVID-19 pandemic, repetitive lung examinations have become
necessary to follow-up symptoms and associated alterations. Low-field MRI, benefiting from …

Validation of automated perfusion‐weighted phase‐resolved functional lung (PREFUL)‐MRI in patients with pulmonary diseases

L Behrendt, A Voskrebenzev, F Klimeš… - Journal of Magnetic …, 2020 - Wiley Online Library
Background Perfusion‐weighted (Qw) noncontrast‐enhanced proton lung MRI is a
promising technique for assessment of pulmonary perfusion, but still requires validation …

Effect of indacaterol/glycopyrronium on pulmonary perfusion and ventilation in hyperinflated patients with chronic obstructive pulmonary disease (CLAIM). A double …

J Vogel-Claussen, CO Schönfeld, TF Kaireit… - American journal of …, 2019 - atsjournals.org
Rationale: In the CLAIM study, dual bronchodilation with indacaterol/glycopyrronium
(IND/GLY) significantly reduced hyperinflation, which translated into improved cardiac …

Repeatability of phase‐resolved functional lung (PREFUL)‐MRI ventilation and perfusion parameters in healthy subjects and COPD Patients

GH Pöhler, F Klimeš, L Behrendt… - Journal of Magnetic …, 2021 - Wiley Online Library
Background Free‐breathing phase‐resolved functional lung (PREFUL)‐MRI may be useful
for treatment monitoring in chronic obstructive pulmonary disease (COPD) patients with …