Mobile genetic elements are key to the evolution of bacteria and traits that affect host and
ecosystem health. Here, we use a framework of a hierarchical and modular system that …

Highlights•Collaboration and conflict between MGEs can promote and inhibit HGT•Many
genome defences are MGE-encoded, serving MGE interests and changing frequently•The …

Pathogenic Acinetobacter species, most notably Acinetobacter baumannii, are a significant
cause of healthcare‐associated infections worldwide. Acinetobacter infections are of …

Antibiotic resistance tends to carry fitness costs, making it difficult to understand how
resistance can be maintained in the absence of continual antibiotic exposure. Here we …

Bacteriophages, viruses that infect and replicate within bacteria, impact bacterial responses
to antibiotics in complex ways. Recent studies using lytic bacteriophages to treat bacterial …

The escalating misuse and excessive utilization of antibiotics have led to the widespread
dissemination of drug-resistant bacteria, posing a significant global healthcare crisis. Of …

India is one of the largest consumers and producers of antibiotics and a hot spot for the
emergence and proliferation of antimicrobial resistance genes (ARGs). Indian hospital …

Bacterial pathogens carrying multidrug resistance (MDR) plasmids are a major threat to
human health. The acquisition of antibiotic resistance genes (ARGs) in plasmids is often …

Hypervirulence and carbapenem-resistant have emerged as two distinct evolutionary
pathotypes of Klebsiella pneumoniae, with both reaching their epidemic success and posing …

High bacterial community diversity and complexity greatly challenge the cost-efficient
monitoring of clinically prevalent antibiotic-resistant bacteria, which are usually present as …