Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema

M Chilosi, A Carloni, A Rossi, V Poletti - Translational Research, 2013 - Elsevier
Different anatomic and physiological changes occur in the lung of aging people that can
affect pulmonary functions, and different pulmonary diseases, including deadly diseases …

Mesenchymal stem cells and the lung

K Sinclair, ST Yerkovich, DC Chambers - Respirology, 2013 - Wiley Online Library
Mesenchymal stem cells (MSC) are a population of tissue‐resident adult progenitor cells
that were originally identified in bone marrow, but have now been identified in many organs …

Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3

Z Zheng, Y Li, S Jia, M Zhu, L Cao, M Tao… - Nature …, 2021 - nature.com
Pre-metastatic niche formation is critical for the colonization of disseminated cancer cells in
distant organs. Here we find that lung mesenchymal stromal cells (LMSCs) at pre-metastatic …

Immunological characterization of multipotent mesenchymal stromal cells—The International Society for Cellular Therapy (ISCT) working proposal

M Krampera, J Galipeau, Y Shi, K Tarte, L Sensebe - Cytotherapy, 2013 - Elsevier
Cultured mesenchymal stromal cells (MSCs) possess immune regulatory properties and are
already used for clinical purposes, although preclinical data (both in vitro and in vivo in …

[HTML][HTML] The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells

J Wang, K De Veirman, N De Beule, K Maes… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Exosomes, extracellular nanovesicles secreted by various cell types, modulate the bone
marrow (BM) microenvironment by regulating angiogenesis, cytokine release, immune …

Effects of different mesenchymal stromal cell sources and delivery routes in experimental emphysema

MA Antunes, SC Abreu, FF Cruz, AC Teixeira… - Respiratory …, 2014 - Springer
We sought to assess whether the effects of mesenchymal stromal cells (MSC) on lung
inflammation and remodeling in experimental emphysema would differ according to MSC …

Therapeutic MSC exosomes are derived from lipid raft microdomains in the plasma membrane

SS Tan, Y Yin, T Lee, RC Lai, RWY Yeo… - Journal of …, 2013 - Taylor & Francis
Background Mesenchymal stem cell (MSC) was previously shown to secrete lipid vesicles
that when purified by high performance liquid chromatography as a population of …

[HTML][HTML] Mesenchymal stromal cells' role in tumor microenvironment: involvement of signaling pathways

AHN Kamdje, PT Kamga, RT Simo… - Cancer biology & …, 2017 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSCs) are adult multipotent stem cells residing as pericytes in
various tissues and organs where they can differentiate into specialized cells to replace …

Bone marrow, adipose, and lung tissue-derived murine mesenchymal stromal cells release different mediators and differentially affect airway and lung parenchyma in …

SC Abreu, MA Antunes, DG Xisto… - Stem cells …, 2017 - academic.oup.com
Mesenchymal stromal cells (MSCs) from different sources have differential effects on lung
injury. To compare the effects of murine MSCs from bone marrow (BM), adipose tissue (AD) …

The effects of endocrine disruptors on adipogenesis and osteogenesis in mesenchymal stem cells: a review

ME Bateman, AL Strong, JA McLachlan… - Frontiers in …, 2017 - frontiersin.org
Endocrine-disrupting chemicals (EDCs) are prevalent in the environment, and
epidemiologic studies have suggested that human exposure is linked to chronic diseases …