Omicron breakthrough infections in wild‐type SARS‐CoV‐2 vaccinees elicit high levels of neutralizing antibodies against pangolin coronavirus GX_P2V

S Lu, S Luo, B Bai, Z Fan, B Hong, W Xu… - Journal of Medical …, 2023 - Wiley Online Library
Omicron BF. 7 became the predominant SARS‐CoV‐2 variant in Beijing after the
abolishment of Zero‐COVID policy in December 2022. The ability of antibodies elicited by …

[HTML][HTML] A Comparative Experimental and Computational Study on the Nature of the Pangolin-CoV and COVID-19 Omicron

L Wei, L Song, AK Dunker, JA Foster… - International Journal of …, 2024 - mdpi.com
The relationship between pangolin-CoV and SARS-CoV-2 has been a subject of debate.
Further evidence of a special relationship between the two viruses can be found by the fact …

An infection and pathogenesis mouse model of SARS-CoV-2-related pangolin coronavirus GX_P2V (short_3UTR)

L Wei, S Liu, S Lu, S Luo, X An, H Fan, W Chen, E Li… - bioRxiv, 2024 - biorxiv.org
SARS-CoV-2-related pangolin coronavirus GX_P2V (short_3UTR) can cause 100%
mortality in human ACE2-transgenic mice, potentially attributable to late-stage brain …

[HTML][HTML] Lethal Infection of Human ACE2-Transgenic Mice Caused by SARS-CoV-2-related Pangolin Coronavirus GX_P2V (short_3UTR)

L Wei, S Liu, S Lu, S Luo, X An, H Fan, W Chen, E Li… - bioRxiv, 2024 - biorxiv.org
SARS-CoV-2-related pangolin coronavirus GX_P2V (short_3UTR) can cause 100%
mortality in human ACE2-transgenic mice, potentially attributable to late-stage brain …

Ultrastructural modifications induced by an attenuated SARS-CoV-2-related pangolin coronavirus GX_P2V (short_3UTR) in Vero cells

L Wei, F Che, S Lu, M Li, X An, H Fan, Y Tong, L Song - 2023 - researchsquare.com
Background Positive-strand RNA viruses, such as SARS-CoV-2, manipulate host cell
endomembranes to form viral replication organelles (vROs) for replication and protection …

The recombinant receptor-binding domain of a pangolin coronavirus spike by prokaryotic expression can partially induce neutralizing antibodies

S Liu, C Chen, S Lu, D Cheng, S Luo, H Fan, Z Chen… - 2023 - researchsquare.com
We previously reported that a SARS-CoV-2 related pangolin coronavirus GX_P2V can
induce neutralizing antibodies against SARS-CoV-2 in a golden hamster model. The two …

A potential broad-spectrum live-attenuated SARS-CoV-2 vaccine derived from pangolin coronavirus and insights into the immune evasion mechanisms of XBB. 1.16 …

L Song, S Lu, S Luo, B Bai, L Jiang, Z Fan, L Wei, L Hai… - 2023 - researchsquare.com
Harnessing SARS-CoV-2 related viruses from wild animals for live vaccines is an
underexplored but promising approach, akin to the vaccinia virus used against smallpox …