Several groups have recently reported evidence for the emergence of domains in cell
plasma membranes when membrane proteins are organized by ligand binding or assembly …

This article summarizes a variety of physical mechanisms proposed in the literature, which
can generate micro-and nanodomains in multicomponent lipid bilayers and biomembranes …

Images of micrometer-scale domains in lipid bilayers have provided the gold standard of
model-free evidence to understand the domains' shapes, sizes, and distributions …

Lateral organization in the plane of the plasma membrane is an important driver of biological
processes. The past dozen years have seen increasing experimental support for the notion …

As a model of lipid rafts, the liquid-ordered (Lo) phase formed by sphingomyelin (SM) and
cholesterol (Cho) in bilayer membranes has long attracted the attention of biophysics …

Cholesterol has been conjectured to be a modulator of the amyloid cascade, the mechanism
that produces the amyloid-β (Aβ) peptides implicated in the onset of Alzheimer's disease …

Cholesterol is a key component of eukaryotic membranes, but its role in cellular biology in
general and in lipid rafts in particular remains controversial. Model membranes are used …

Liquid-ordered lipid domains, also called rafts, are assumed to be important players in
different cellular processes, mainly signal transduction and membrane trafficking. They are …

Cholesterol is essential to the formation of phase-separated lipid domains in membranes.
Lipid domains can exist in different thermodynamic phases depending on the molecular …

Membrane phase-separation is a mechanism that biological membranes often use to locally
concentrate specific lipid species in order to organize diverse membrane processes. Phase …