The majority of enzymes in the sphingolipid (SL) biosynthetic pathway have been identified
over the past couple of decades. Despite significant work, and despite their crucial and …

Interest in macropinocytosis has risen in recent years owing to its function in tumorigenesis,
immune reaction, and viral infection. Cancer cells utilize macropinocytosis to acquire …

Background Synthetic indolyl-pyridinyl-propenones (IPPs) induce methuosis, a form of non-
apoptotic cell death, in glioblastoma and other cancer cell lines. Methuosis is characterized …

The volumes of a cell [cell volume (CV)] and its organelles are adjusted by osmoregulatory
processes. During pinocytosis, extracellular fluid volume equivalent to its CV is incorporated …

Simple Summary Osteosarcoma (OS) is a primary malignant tumor of bone.
Macropinocytosis, a form of non-selective nutrient endocytosis, has received increasing …

Methuosis is a type of programmed cell death in which the cytoplasm is occupied by fluid-
filled vacuoles that originate from macropinosomes (cytoplasmic vacuolation). A few …

There has been growing interest in investigating anti-tumor drugs that not only kill cancer
cells but also stimulate the immune system, among them, necroptosis is a classical …

Autophagy is an elegant and complex biological process that has recently attracted much
attention from the scientific community. The compounds which are capable of control and …

Transition metal catalysis has contributed to the discovery of novel methodologies and the
preparation of natural products, as well as new chances to increase the chemical space in …

Maduramicin frequently induces severe cardiotoxicity in target and nontarget animals in
clinic. Apoptotic and non‐apoptotic cell death mediate its cardiotoxicity; however, the …