Plants can be engineered to recombinantly produce high-quality proteins such as
therapeutic proteins and vaccines, also known as molecular farming. Molecular farming can …

Protein glycosylation has a huge impact on biological processes in all domains of life. The
type of glycan present on a recombinant glycoprotein depends on protein intrinsic features …

Immune checkpoint inhibitors (ICIs) have achieved huge clinical success. However, many
still have limited response rates, and are prohibitively costly. There is a need for effective …

The emergence of Omicron lineages and descendent subvariants continues to present a
severe threat to the effectiveness of vaccines and therapeutic antibodies. We have …

Passive delivery of antibodies to mucosal sites may be a valuable adjunct to COVID-19
vaccination to prevent infection, treat viral carriage, or block transmission. Neutralizing …

Immunoglobulin M (IgM) is the largest antibody isotype with unique features like extensive
glycosylation and oligomerization. Major hurdles in characterizing its properties are …

Developing effective therapeutics or preventive interventions for important health threats is
greatly enhanced whenever accessible models can enable the assessment of clinically …

Antimicrobial resistance (AMR) is one of the most critical threats to global public health in the
21st century, causing a large number of deaths every year in both high-income and low-and …

Eliminating diarrheal diseases as a leading cause of childhood morbidity and mortality in
low-and middle-income countries (LMICs) will require multiple intervention strategies. In this …

肠道微生物伴随宿主一生, 对宿主的消化吸收以及肠道健康产生巨大影响.
肠道微生物的动态平衡维护宿主稳态, 而肠道微生物失调会引起宿主肠道相关疾病 …