Current state and challenges in developing oral vaccines

JEV Ramirez, LA Sharpe, NA Peppas - Advanced drug delivery reviews, 2017 - Elsevier
While vaccination remains the most cost effective strategy for disease prevention,
communicable diseases persist as the second leading cause of death worldwide. There is a …

Platforms for production of protein-based vaccines: from classical to next-generation strategies

R Cid, J Bolívar - Biomolecules, 2021 - mdpi.com
To date, vaccination has become one of the most effective strategies to control and reduce
infectious diseases, preventing millions of deaths worldwide. The earliest vaccines were …

Native‐like Env trimers as a platform for HIV‐1 vaccine design

RW Sanders, JP Moore - Immunological reviews, 2017 - Wiley Online Library
We describe the development and potential use of various designs of recombinant HIV‐1
envelope glycoprotein trimers that mimic the structure of the virion‐associated spike, which …

A state-of-the-art review on solid lipid nanoparticles as a nanovaccines delivery system

M Assefi, M Ataeinaeini, A Nazari, A Gholipour… - Journal of Drug Delivery …, 2023 - Elsevier
In the design of vaccine generation, significant attempts have been made to produce novel
vaccines and, as well, to increase the effectiveness of available vaccines versus particular …

Antimicrobial resistance in livestock: advances and alternatives to antibiotics

RR Marquardt, S Li - Animal Frontiers, 2018 - academic.oup.com
Antimicrobial resistance in livestock: advances and alternatives to antibiotics | Animal Frontiers |
Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals Books Search …

Hydrogel-forming microneedles with applications in oral diseases management

Y Li, D Bi, Z Hu, Y Yang, Y Liu, WK Leung - Materials, 2023 - mdpi.com
Controlled drug delivery in the oral cavity poses challenges such as bacterial contamination,
saliva dilution, and inactivation by salivary enzymes upon ingestion. Microneedles offer a …

Comparative immunogenicity of the recombinant receptor-binding domain of protein S SARS-CoV-2 obtained in prokaryotic and mammalian expression systems

IA Merkuleva, DN Shcherbakov, MB Borgoyakova… - Vaccines, 2022 - mdpi.com
The receptor-binding domain (RBD) of the protein S SARS-CoV-2 is considered to be one of
the appealing targets for developing a vaccine against COVID-19. The choice of an …

Technological microbiology: development and applications

LC Vitorino, LA Bessa - Frontiers in Microbiology, 2017 - frontiersin.org
Over thousands of years, modernization could be predicted for the use of microorganisms in
the production of foods and beverages. However, the current accelerated pace of new food …

Biotechnology approaches to produce potent, self-adjuvanting antigen-adjuvant fusion protein subunit vaccines

PM Moyle - Biotechnology advances, 2017 - Elsevier
Traditional vaccination approaches (eg live attenuated or killed microorganisms) are among
the most effective means to prevent the spread of infectious diseases. These approaches …

A fast-dissolving microneedle array loaded with chitosan nanoparticles to evoke systemic immune responses in mice

Z Li, Y He, L Deng, ZR Zhang, Y Lin - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Microneedle (MN) arrays offer an alternative approach to hypodermic injection via syringe
needles. In this work, polyvinylpyrrolidone (PVP)-based fast dissolving MN arrays were …